| Identification | More | [Name]
LACTAMIDE | [CAS]
2043-43-8 | [Synonyms]
2-HYDROXYPROPIONAMIDE
AURORA KA-7344
DL-LACTAMIDE
DL-LACTIC ACID AMIDE
LACTAMIDE
2-Hydroxypropanamide
alpha-Hydroxypropionamide
Lactic acid amide
Lactic amide
L-(-)-LACTAMIDE 99+%
Propanamide, 2-hydroxy- | [EINECS(EC#)]
218-049-3 | [Molecular Formula]
C3H7NO2 | [MDL Number]
MFCD00008017 | [Molecular Weight]
89.09 | [MOL File]
2043-43-8.mol |
| Chemical Properties | Back Directory | [Melting point ]
73-76 °C(lit.) | [Boiling point ]
165.17°C (rough estimate) | [density ]
1.1948 (rough estimate) | [refractive index ]
1.4368 (estimate) | [form ]
powder to crystal | [pka]
13.34±0.20(Predicted) | [color ]
White to Almost white | [Water Solubility ]
782.20g/L(25 ºC) | [LogP]
-1.161 (est) | [CAS DataBase Reference]
2043-43-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HS Code ]
2924.19.8000 |
| Hazard Information | Back Directory | [Uses]
Lactamide is used as a synthetic raw material in organic chemistry, as an additive in cosmetics, and as a preservative in frozen semen and fertilized eggs in livestock reproduction studies. | [Definition]
ChEBI:Lactamide is a monocarboxylic acid amide that is lactic acid
in which the carboxylic acid group has been converted to the
corresponding carboxamide. It is a monocarboxylic acid amide and a
secondary alcohol. It is functionally related to a rac-lactic acid. | [Synthesis]
α-Hydroxy methyl ester (10 mmol, 1.0 equiv) was added into the 100 ml RBF, anda saturated methanol solution of ammonia (20 ml, 38 equiv) was added underthe ice-water bath and stirred overnight. The mixture was concentrated underreduced pressure and in most case Lactamide were obtained in high yields,while in rare occasions purified by flash chromatography. |
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