| Identification | More | [Name]
(3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate | [CAS]
201856-57-7 | [Synonyms]
3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-dimethylethyl ester
(3r,4s)-tert-butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate
(3R,4S)-1-AZETIDINECARBOXYLIC ACID-3-(2-ETHOXYETHOXY)-4-PHENYL-2-PHENYL-AZETIDIONE
(3R,4S)-1-t-butoxycarbonyl-3-(2-ethoxyethoxyl)-4-phenyl-2-azetidinone
(3R,4S)-1-T-BUTOXYCARBONYL-3-(2-ETHOXYETHOXYL)-4-PHENYL-2-AZETIDINONE,98+%
SIDE CHAINS OF DOCETAXEL--1 | [EINECS(EC#)]
1592732-453-0 | [Molecular Formula]
C18H25NO5 | [Molecular Weight]
335.39 | [MOL File]
201856-57-7.mol |
| Hazard Information | Back Directory | [Uses]
(3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-Dimethylethyl ester is used as a reagent in the synthesis of abeo-taxane derivatives that possess broad inhibitory effects against proliferation of colon cancer, melanoma, and renal cancer cell lines. (3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-Dimethylethyl ester is also used as a reagent in the synthesis of a novel D-ring modified Docetaxel (D494420) analogue which has proven to have equipotent cytotoxicity in relation to Paclitaxel (P132500) towards cancer cell lines. |
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