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ChemicalBook--->CAS DataBase List--->2016-36-6

2016-36-6

2016-36-6 Structure

2016-36-6 Structure
IdentificationBack Directory
[Name]

Choline salicylate
[CAS]

2016-36-6
[Synonyms]

arret
actasal
salicol
satibon
mundisal
arthropan
artrobione
COL SALICYLAT
COL SALICYLATE
BASIONIC FS 65
Basionics? FS 65
CHOLIN SALICYLATE
BASIONIC(TM) FS 65
CHOLINE SALICYLATE
cholinesalicylateb
cholinesalicylicacidsalt
choline,salicylate(salt)
salicylicacidcholinesalt
salicylicacid,ion(1-),choline
BASIONIC(R) FS 65, COL Salicylat
(2-hydroxyethyl)trimethylammoniumsalicylate
2-carboxyphenolate,2-hydroxyethyl(trimethyl)azanium
2-Hydroxy-N,N,N-trimethylethanaminium/salicylate,(1:1)
2-Hydroxy-N,N,N-trimethylethanaminium 2-hydroxybenzoate
2-hydroxy-n,n,n-trimethyl-ethanaminiusaltwith2-hydroxybenzoicacid(1:
2-hydroxy-n,n,n-trimethyl-ethanaminiusaltwith2-hydroxybenzoicacid(1:1)
2-hydroxy-n,n,n-trimethylethanaminiumsaltwith2-hydroxybenzoicacid(1:1)
Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 2-hydroxybenzoic acid (1:1)
[EINECS(EC#)]

217-948-8
[Molecular Formula]

C12H19NO4
[MDL Number]

MFCD00242760
[MOL File]

2016-36-6.mol
[Molecular Weight]

241.28
Chemical PropertiesBack Directory
[Melting point ]

49.5-50.0°
[Boiling point ]

384.06°C (rough estimate)
[density ]

1.1442 (rough estimate)
[refractive index ]

1.4596 (estimate)
[Fp ]

183 °C
[storage temp. ]

Hygroscopic, Refrigerator, under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

Colourless to Light Brown Oil
[Stability:]

Hygroscopic
[EPA Substance Registry System]

Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 2-hydroxybenzoic acid (1:1) (2016-36-6)
Safety DataBack Directory
[WGK Germany ]

2
[RTECS ]

GA6475000
[F ]

3-10
Hazard InformationBack Directory
[Description]

Choline salicylate is absorbed more rapidly than aspirin and produces higher salicylate plasma levels. It is available as a mint-flavored liquid.
[Originator]

Arthropan ,Purdue , US,1959
[Uses]

Choline Salicylate displays protective effects in the treatment of Alzheimer’s disease. It has the potential to relieve pain associated with mouth ulcers.
[Definition]

ChEBI: Choline salicylate is a hydroxybenzoic acid. It is functionally related to a salicylic acid.
[Manufacturing Process]

A method of preparation is to react an acid salt of choline (such as choline chloride or choline bromide) with an alkaline salt of salicylic acid (such as sodium salicylate, potassium salicylate, or magnesium salicylate) in an alcoholic media.
[Brand name]

Arthropan (Purdue Frederick).
[Therapeutic Function]

Analgesic; Antipyretic
[Clinical Use]

Choline salicylate has a lower incidence of GI side effects compared with aspirin, and it has been shown to be particularly useful in treating juvenile rheumatoid arthritis, in which aspirin was ineffective.
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