| Identification | More | [Name]
Fmoc-S-Trityl-L-penicillamine | [CAS]
201531-88-6 | [Synonyms]
FMOC-BETA,BETA-DIMETHYL-CYS(TRT)-OH
FMOC-CYSME 2(TRT)-OH
FMOC-L-PEN(TRT)-OH
FMOC-PENICILLAMINE(TRT)-OH
FMOC-PEN(TRT)-OH
FMOC-S-TRITYL-BETA,BETA-DIMETHYL-L-CYS-OH
FMOC-S-TRITYL-L-PENICILLAMINE
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-S-TRITYL-3,3-DIMETHYL-L-CYSTEINE
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-S-TRITYL-L-PENICILLAMINE
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-S-TRITYL-L-PENICILLAMINE
N-ALPHA-FMOC-S-TRITYL-L-PENICILLAMINE
N-alpha-(9-Fluorenylmethyloxycarbonyl)-S-trityl-L-penicillamine, Fmoc-beta,beta-dimethyl-L-Cys(Trt)-OH
Fmoc-β,β-dimethyl-Cys(Trt)-OH, Fmoc-S-trityl-L-penicillamine | [Molecular Formula]
C39H35NO4S | [MDL Number]
MFCD00237388 | [Molecular Weight]
613.76 | [MOL File]
201531-88-6.mol |
| Hazard Information | Back Directory | [Description]
Fmoc-S-trityl-L-penicillamine is a coordination compound that contains a thiolate and amide group. It has been used as a model system for studying the interaction between proteins and metal ions, with the cyclic structure mimicking the active site of enzymes. The coordination of Fmoc-S-trityl-L-penicillamine to proteins is affected by trypsin, an enzyme that cleaves peptides at carboxyl side chains. Trypsin can also lead to dehydration of Fmoc-S-trityl-L-penicillamine, forming an eliminations product. This compound also reacts with lysine residues in proteins, resulting in an alkene byproduct that can be removed by hydrogenation. | [Chemical Properties]
White to off-white powder | [Uses]
Fmoc-s-trityl-l-penicillamine is a new peptidomimetic furin inhibitors with potent anti-infectious activity. |
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