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ChemicalBook--->CAS DataBase List--->18711-16-5

18711-16-5

18711-16-5 Structure

18711-16-5 Structure
IdentificationBack Directory
[Name]

NS309
[CAS]

18711-16-5
[Synonyms]

NS 309; NS-309
NS309;NS 309;NS-309
6,7-Dichloroisatin 3-oxime
6,7-Dichloroindole-2,3-dione 3-oxime
6,7-Dichloro-1H-indole-2,3-dione3-oxime
6,7-Dichloro-3-(hydroxyiMino)indolin-2-one
1H-Indole-2,3-dione,6,7-dichloro-, 3-oxiMe
[Molecular Formula]

C8H4Cl2N2O2
[MDL Number]

MFCD06798346
[MOL File]

18711-16-5.mol
[Molecular Weight]

231.04
Chemical PropertiesBack Directory
[Melting point ]

190-192℃
[storage temp. ]

2-8°C
[solubility ]

DMSO: ~22 mg/mL
[form ]

solid
[color ]

yellow
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

2
Hazard InformationBack Directory
[Uses]

NS 309 decreases rat detrusor smooth muscle membrane potential and phasic contractions by activating SK3 channels.
[Biological Activity]

Positive modulator of small- and intermediate- conductance Ca 2+ -activated K + channels (SK and IK channels); increases Ca 2+ sensitivity. Displays no activity at BK channels.
[Biochem/physiol Actions]

NS309 is a Ca2+-activated IK/SK potassium channel activator.
[storage]

+4°C
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