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ChemicalBook--->CAS DataBase List--->183364-82-1

183364-82-1

183364-82-1 Structure

183364-82-1 Structure
IdentificationBack Directory
[Name]

CPPG
[CAS]

183364-82-1
[Synonyms]

CPPG
rac-CPPG
(RS)-CPPG
(RS)-α-Cyclopropyl-4-phosphonophenylglycine
(RS)-ALPHA-CYCLOPROPYL-4-PHOSPHONOPHENYLGLYCINE
(+/-)-ALPHA-CYCLOPROPYL-4-PHOSPHONOPHENYLGLYCINE
Benzeneacetic acid, α-amino-α-cyclopropyl-4-phosphono-
[Molecular Formula]

C11H14NO5P
[MDL Number]

MFCD00673967
[MOL File]

183364-82-1.mol
[Molecular Weight]

271.21
Chemical PropertiesBack Directory
[storage temp. ]

Store at RT
[solubility ]

H2O: >5mg/mL
[form ]

Solid
[color ]

white to beige
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P264-P270-P301+P312-P330-P501
[Hazard Codes ]

Xn
[Risk Statements ]

22
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

(RS)-CPPG is the most potent group II/III mGluR antagonist.
[Definition]

ChEBI: 2-amino-2-cyclopropyl-2-(4-phosphonophenyl)acetic acid is an alpha-amino acid.
[Biological Activity]

Potent group II/III mGlu receptor antagonist, with approximately 20-fold selectivity for group III over group II (IC 50 values of 2.2 and 46.2 nM respectively). A much less potent antagonist at group I receptors in neonatal rat cortical slices (K b = 0.65 ± 0.07 nM). Also available as part of the Group III mGlu Receptor Tocriset™ .
[storage]

Room temperature
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