Identification | More | [Name]
1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | [CAS]
18194-24-6 | [Synonyms]
1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE 1,2-DITETRADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 14:0 PC BETA-GAMMA-DIMYRISTOYL-L-ALPHA-LECITHIN DIMYRISTOYL-L-3-LECITHIN DIMYRISTOYL LECITHIN DMPC L-ALPHA-PHOSPHATIDYLCHOLINE, DIMYRISTOYL L-ALPHA-PHOSPHATIDYLCHOLINE, DIMYRISTOYL (C14:0) L-BETA,GAMMA-DIMYRISTOYL-ALPHA-LECITHIN dimyristoyl l-a-phosphatidylcholinedimyristoyl (R)-(7-myristoyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphatricosyl)trimethylammonium 4-oxide L-a-Lecithin-b,g-dimyristoyl=b,g-Dimyristoyl-L-a-Lecithin=Dimyristoyl-L-a-Lecithin=Dimyristoyl-L-3-Lecithin Lecithin-b,g-Dimyristoyl-L-a-=Dimyristoyl-L-a-L 1,2-Dimyristoyl-SN-Glycero-3-Phospho-Choline-D54 DIMYRISTOYL-L-3-LECITHIN Synthetic 1,2-Ditetradecanoyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-dimyristoyl, L-β,γ-Dimyristoyl-α-lecithin | [EINECS(EC#)]
242-085-9 | [Molecular Formula]
C36H72NO8P | [MDL Number]
MFCD00036901 | [Molecular Weight]
677.93 | [MOL File]
18194-24-6.mol |
Chemical Properties | Back Directory | [Appearance]
white powder | [Melting point ]
220°C(lit.) | [storage temp. ]
−20°C
| [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Stability:]
Stable, but heat sensitive-store at-20 C. Incompatible with strong oxidizing agents. | [BRN ]
3921768 | [InChIKey]
CITHEXJVPOWHKC-UUWRZZSWSA-N | [CAS DataBase Reference]
18194-24-6(CAS DataBase Reference) |
Hazard Information | Back Directory | [Description]
1,2-Dimyristoyl-sn-glycero-3-PC (DMPC) is a phospholipid containing 14:0 fatty acids at the sn-1 and sn-2 positions. It is a synthetic phosopholipid that has been used for liposome production in order to study the properties of lipid bilayer.1,2,3 | [Chemical Properties]
white powder | [Uses]
1,2-dimyristoyl-sn-glycero-3-phosphocholine is a phospholipid containing 14:0 fatty acids at the sn-1 and sn-2 positions. It is a synthetic phosopholipid that can be used for liposome production in order to study the properties of lipid bilayer.[Cayman Chemical]
| [Definition]
ChEBI: A 1,2-diacyl-sn-glycero-3-phosphocholine where the two phosphatidyl acyl groups are specified as tetradecanoyl (myristoyl). | [General Description]
Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon. | [Biochem/physiol Actions]
Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides. | [Purification Methods]
It has three forms 1, 2 and '. Recrystallise it from aqueous EtOH or EtOH/Et2O. Its solubility at 22-23o in Et2O is 0.03%, in Me2CO it is 0.06% and in pyridine it is 1.3%. [Baer & Kates J Am Chem Soc 72 942 1950, Baer & Maurakas J Am Chem Soc 74 158 1952, IR: Marinetti & Stotz J Am Chem Soc 76 1347 1954.] The S-isomer with 1H2O is recrystallised from 2,6-dimethylheptan-4-one and has m 226-227o (sintering at 90-95o), and [] 20D -7o (c 6, MeOH/CHCl3 1:1). [Baer & Martin J Biol Chem 193 835 1951, Beilstein 4 IV 1463.] |
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