| Identification | More | [Name]
4-PHENYL-3-BUTYN-2-ONE | [CAS]
1817-57-8 | [Synonyms]
4-PHENYL-3-BUTYN-2-ONE
1-Phenyl-1-butyn-3-one
3-Butyn-2-one, 4-phenyl-
4-Phenyl-3-batyu-2-one
4-phenyl-3-butyn-2-on
Phenylbutynone
4-phenylbut-3-yn-2-one
4-phenyl-3-butyn-2-0ne
4-PHENYL-3-BUTYN-2-ONE 97+%
1-Acetyl-2-phenylethyne
1-Phenyl-2-acetylacetylene | [EINECS(EC#)]
217-327-1 | [Molecular Formula]
C10H8O | [MDL Number]
MFCD00008776 | [Molecular Weight]
144.17 | [MOL File]
1817-57-8.mol |
| Chemical Properties | Back Directory | [Melting point ]
4°C | [Boiling point ]
75-76 °C/0.8 mmHg (lit.) | [density ]
0.99 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.574(lit.)
| [Fp ]
203 °F
| [storage temp. ]
2-8°C | [form ]
clear liquid | [color ]
Colorless to Yellow to Green | [Specific Gravity]
1.02 | [Water Solubility ]
Insoluble in water. | [CAS DataBase Reference]
1817-57-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S27:Take off immediately all contaminated clothing .
S37/39:Wear suitable gloves and eye/face protection . | [RIDADR ]
UN 3334 | [WGK Germany ]
3
| [RTECS ]
ES0890000
| [HS Code ]
2914390090 | [Toxicity]
mouse,LD50,intravenous,56mg/kg (56mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#05642, |
| Hazard Information | Back Directory | [Uses]
It is used as pharmaceutical intermediate. | [Definition]
ChEBI: 4-phenylbut-3-yn-2-one is a ynone. | [Synthesis Reference(s)]
Chemistry Letters, 9, p. 1327, 1980
The Journal of Organic Chemistry, 47, p. 2549, 1982 DOI: 10.1021/jo00134a010
Tetrahedron Letters, 29, p. 2321, 1988 DOI: 10.1016/S0040-4039(00)86048-7 | [General Description]
4-Phenyl-3-butyn-2-one is an α,β-ketoalkyne. Reaction of 4-phenyl-3-butyn-2-one with bromine chloride and iodine monochloride in CH2Cl2, CH2Cl2/pyridine and MeOH are studied. Reduction of 4-phenyl-3-butyn-2-one in THF solution has been reported. |
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