| Identification | Back Directory | [Name]
N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine | [CAS]
179552-74-0 | [Synonyms]
Afatinib Impurity 137
N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitro-4-Quinazolinamine
4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitro-
(3-chloro-4-fluoro-phenyl)-(7-methoxy-6-nitro-quinazolin-4-yl)-amine | [EINECS(EC#)]
207-985-8 | [Molecular Formula]
C15H10ClFN4O3 | [MOL File]
179552-74-0.mol | [Molecular Weight]
348.72 |
| Chemical Properties | Back Directory | [Boiling point ]
515.5±50.0 °C(Predicted) | [density ]
1.529±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [pka]
5.07±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine is a useful synthetic intermediate in the synthesis of Afatinib (A355300); an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder. |
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