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ChemicalBook--->CAS DataBase List--->1781882-65-2

1781882-65-2

1781882-65-2 Structure

1781882-65-2 Structure
IdentificationBack Directory
[Name]

Pyridostatin hydrochloride
[CAS]

1781882-65-2
[Synonyms]

Pyridostatin HCl
RR-82 hydrochloride
Pyridostatin hydrochloride
[Molecular Formula]

C5H6ClNSn8
[MOL File]

1781882-65-2.mol
[Molecular Weight]

1065.24
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[form ]

Solid
[color ]

White to off-white
[Water Solubility ]

Water: 50 mg/mL (64.19 mM)
Hazard InformationBack Directory
[Biological Activity]

Pyridostatin (RR82) hydrochloride is a highly selective G-quadruplex DNA stabilizer (Kd=490 nM). It promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage.
[in vitro]

Pyridostatin (RR82) hydrochloride (10 μM; 48 hours) induces cell cycle arrest. It is a very selective G-quadruplex DNA-binding small molecule designed to form a complex with and stabilize G-quadruplex structure.
[target]

Kd: 490 nM (G-quadruplexe)

[storage]

Store at -20°C
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