Identification | Back Directory | [Name]
METHOXYVERAPAMIL HYDROCHLORIDE | [CAS]
16662-47-8 | [Synonyms]
C13764 dl-D 600 Lu 30-029 CoMpound D 600 Methoxyverapamil D 600 (vasodilator) (+/-)-Methoxyverapamil (+/-)-MethoxyverapamilHydrochloride (±)-Methoxyverapamil hydrochloride Solution, 100ppm (±)-Methoxyverapamil hydrochloride Solution, 1000ppm (+/-)-METHOXYVERAPAMIL HYDROCHLORIDE (D6 00) (GALLOPAMIL) 5-[(3,4-Dimethoxyphenethyl)methylamino]-2-isopropyl-2-(3,4,5-trimethoxyphenyl)valeronitrile 5-((3,4-diMethoxyphenethyl)(Methyl)aMino)-2-isopropyl-2-(3,4,5-triMethoxyphenyl)pentanenitrile 5-((3,4-diMethoxyphenethyl)(Methyl)aMino)-2-isopropyl-2-(3,4,5-triMethoxyphenyl)pentanenitrile HCl 5-[[2-(3,4-Dimethoxyphenyl)ethyl](methyl)amino]-2-isopropyl-2-(3,4,5-trimethoxyphenyl)pentanenitrile α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4,5-trimethoxy-α-isopropylbenzeneacetonitrile α-[3-[N-[2-(3,4-Dimethoxyphenyl)ethyl]-N-methylamino]propyl]-3,4,5-trimethoxy-α-isopropylbenzeneacetonitrile Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4,5-trimethoxy-α-(1-methylethyl)- (±)-α-[3-[(2-(3,4-dimethoxyphenyl)ethyl)methylamino]propyl]-3,4,5-trimethoxy-α-(1-methylethyl)benzeneacetonitrile hydrochloride D600, Gallopamil, (±)-α-[3-[(2-(3,4-Dimethoxyphenyl)ethyl)methylamino]propyl]-3,4,5-trimethoxy-α-(1-methylethyl)benzeneacetonitrile hydrochloride | [Molecular Formula]
C28H40N2O5 | [MDL Number]
MFCD00058000 | [MOL File]
16662-47-8.mol | [Molecular Weight]
484.63 |
Chemical Properties | Back Directory | [Boiling point ]
605.9±55.0 °C(Predicted) | [density ]
1.068±0.06 g/cm3(Predicted) | [refractive index ]
nD25 1.5402 | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 100 mg/mL (206.34 mM) | [form ]
White to off-white solid. | [pka]
8.96±0.50(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
(±)-Methoxyverapamil hydrochloride has been used:
- as calcium channel antagonist in Schistosoma mansoni parasite
- as calcium entry blocker in cultured macrophages
- in the inhibition of L-type voltage gated Ca2+-channels
| [Definition]
ChEBI: Gallopamil is a member of benzenes and an organic amino compound. | [General Description]
Methoxyverapamil is a calmodulin antagonist. It controls flagellar glycoprotein redistribution by modulating calcium signalling. Methoxyverapamil impacts the effect of intracellular calcium levels and affects the sperm capacitation function. | [Biochem/physiol Actions]
Blocks L-type Ca2+ channels | [Side effects]
Gallopamil has a distinctly stronger effect
than verapamil but a similar activity profile ,
. |
|
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Acesys Pharmatech
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18860950986 |
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Sigma-Aldrich
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Energy Chemical
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cjbscvictory
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