Identification | More | [Name]
Tetraisopropyl methylenediphosphonate | [CAS]
1660-95-3 | [Synonyms]
METHYLENEDIPHOSPHONIC ACID TETRAISOPROPYL ESTER TETRAISOPROPYL(METHYLENE)BISPHOSPHONATE TETRAISOPROPYL METHYLENEDIPHOSPHONATE Phosphonic acid, methylenebis-, tetrakis(1-methylethyl) ester Phosphonic acid, methylenedi-, tetraisopropyl ester phosphonicacid,methylenebis-,tetrakis(1-methylethyl)ester tetra-i-Propylmethylenediphosphonate Methanediphosphonic acid tetraisopropyl ester Tetra isopropyl methylene diphospshonate METHYLENEBIS-PHOSPHONICACID,TETRAKIS(1-METHYLETHYL)ESTER METHYLENEPHOSPHONIC ACID TETRAISOPROPYL ESTER Tetraisopropyl(methylene)bisphosphonate, 98 % 2-[Di(propan-2-yloxy)phosphorylmethyl-propan-2-yloxyphosphoryl]oxypropane Bis(diisopropoxyphosphinyl)methane Tetraisopropyl Methylenediphonate | [EINECS(EC#)]
216-765-0 | [Molecular Formula]
C13H30O6P2 | [MDL Number]
MFCD00015021 | [Molecular Weight]
344.32 | [MOL File]
1660-95-3.mol |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R41:Risk of serious damage to eyes. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . S39:Wear eye/face protection . | [WGK Germany ]
3
| [TSCA ]
Yes | [HS Code ]
29319090 |
Hazard Information | Back Directory | [Chemical Properties]
Clear colorless to slightly yellow liquid | [Uses]
Tetraisopropyl methylenediphosphonate [T(iPr)MDP] forms a synergistic mixture with hydrogen dicarbollylcobaltate in nitrobenzene which was used in the extraction of europium and americium. It may be used in the synthesis of the following:
- tetraisopropyl ethenylidenebisphosphonate.
- tetraisopropyl 4-acetylthiobutane-1,1-diphosphonate
- tetraisopropyl 2-(3,5-bis(bromomethyl)phenyl)ethane-1,1-diphosphonate
| [Uses]
Tetraisopropyl Methylenediphosphonate is used in the preparation of E2-bisphosphonate conjugates as potential anti-osteoporosis agents. Also used in the preparation of AZT 5’-Triphosphate compounds which display inhibitory effects on HIV-1 reverse transcrpitase. | [General Description]
Tetraisopropyl methylenediphosphonate (IPCP) is a tetraisopropyl ester of methylenediphosphonic acid. It is an electroneutral ligand, reported to be synthesized from triisopropyl phosphate. Powder electron paramagnetic resonance (EPR) studies of tris complexes of Cu(II) complexes with IPCP has been analyzed. |
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