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ChemicalBook--->CAS DataBase List--->163437-14-7

163437-14-7

163437-14-7 Structure

163437-14-7 Structure
IdentificationMore
[Name]

FMOC-MET(O2)-OH
[CAS]

163437-14-7
[Synonyms]

FMOC-MET(O2)-OH
FMOC-L-MET(O2)-OH
FMOC-METHIONINE(O2)-OH
FMOC-L-METHIONINE-SULFONE
N-FMoc-L-Methionine sulfone, 98%
N-ALPHA-FMOC-L-METHIONINE-SULFONE
Fmoc-L-methionine sulfone≥ 98% (HPLC)
FMoc-Met(O)2-OH FMoc-L-Methionine sulfone
(9H-Fluoren-9-yl)MethOxy]Carbonyl Met(O2)-OH
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-METHIONINE SULFONE
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-METHIONINESULFON
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-METHIONINESULFONE
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylsulfonylbutanoic acid
(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-(methylsulfonyl)butanoic acid
(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methanesulfonylbutanoic acid
Butanoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-4-(methylsulfonyl)-, (2S)-
[Molecular Formula]

C20H21NO6S
[MDL Number]

MFCD00153361
[Molecular Weight]

403.45
[MOL File]

163437-14-7.mol
Chemical PropertiesBack Directory
[Boiling point ]

709.5±60.0 °C(Predicted)
[density ]

1.359
[storage temp. ]

Store at RT.
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
[pka]

3.52±0.10(Predicted)
[color ]

White
[InChIKey]

KJLKPACOHZKRFM-SFHVURJKSA-N
[CAS DataBase Reference]

163437-14-7(CAS DataBase Reference)
Safety DataBack Directory
[WGK Germany ]

WGK 2 water endangering
[HS Code ]

2930 90 98
Questions and Answers (Q&A)Back Directory
[Description]

FMOC-Met (O2)-OH is the N-alpha protected form of L-methionine mediated by FMOC group (9-Fluorenylmethyloxycarbonyl). It is useful to act as a building block in peptide synthesis. For example, it, as well as its derivative Tbfmoc-Met-OH can be used as a building block for the solid phase synthesis of ubiquitin C-hydrazide. It can also be used for synthesizing some novel cyclic peptides with pharmacological effects such as treatment of inflammatory disease.
[References]

http://www.sigmaaldrich.com/technical-documents/articles/chemfiles/natural-amino-acid.html
https://www.iris-biotech.de/de/faa1490/Anderson, S. N., et al. "Microarrayed compound screening (microARCS) to identify activators and inhibitors of AMP-activated protein kinase."Journal of Biomolecular Screening 9.2(2004):112-121.
http://web.b.ebscohost.com/abstract?direct=true&profile=ehost&scope=site&authtype=crawler&jrnl=09707077&AN=103358230&=iEFjDXbrcrGANWWK7vpLdmsN8yhCmNraNdm1aLMwCgXjuCpr9xSGhioVTsYZqXmo5JtrShPp2WNBkVHpx75ovQ%3d%3d&crl=c&resultNs=AdminWebAuth&resultLocal=ErrCrlNotAuth&crlhashurl=login.aspx%3fdirect%3dtrue%26profile%3dehost%26scope%3dsite%26authtype%3dcrawler%26jrnl%3d09707077%26AN%3d103358230
http://www.google.com/patents/US6511961
Hazard InformationBack Directory
[Chemical Properties]

White powder
[reaction suitability]

reaction type: Fmoc solid-phase peptide synthesis
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76265-70-8 163437-14-7 71989-28-1 7314-32-1 3226-65-1

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