Identification | More | [Name]
(3-Hydroxy-3H-1,2,3-triazolo[4,5-b]pyridinato-O)tri-1-pyrrolidinylphosphonium hexafluorophosphate | [CAS]
156311-83-0 | [Synonyms]
(7-AZABENZOTRIAZOL-1-YLOXY)TRIPYRROLIDINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE 7-AZABENZOTRIAZOL-1-YLOXY-TRIS-(PYRROLIDINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE (7-AZABENZOTRIAZOLE-1-YLOXY)TRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE PYAOP (7-AZABENZOTRIAZOLE-1-YLOXY)TRIPYRROLIDI (7-Azabenzotriazol-1-yloxy)tripyrrolidinophospho PY (7-AZABENZOTRIAZOL-1-YLOXY)TRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE (3-Hydroxy-3H-1,2,3-triazolo[4,5-b]pyridinato-O)tri-1-pyrrolidinylphosphonium hexafluorophosphate PVP-VACOPOLYMERSERIES PYAOP ((7-AZABENZOTRIAZOL-1-YLOXY)TRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE) 3H-1,2,3-triazolo[4,5-b]pyridine phosphonium derivative | [EINECS(EC#)]
627-192-4 | [Molecular Formula]
C17H27F6N7OP2 | [MDL Number]
MFCD03703417 | [Molecular Weight]
521.38 | [MOL File]
156311-83-0.mol |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [HS Code ]
29339900 |
Hazard Information | Back Directory | [Chemical Properties]
(3-Hydroxy-3H-1,2,3-triazolo[4,5-b]pyridinato-O)tri-1-pyrrolidinylphosphonium hexafluorophosphate is white to off-white crystalline powder
| [Uses]
(3-Hydroxy-3H-1,2,3-triazolo[4,5-b]pyridinato-O)tri-1-pyrrolidinylphosphonium hexafluorophosphate is used as a coupling reagent in solid phase peptide synthesis. It is preferred over HATU, because it does not side react at the N-terminus of the peptide. Compared to the HOBt derivates, PyAOP (and HOAt in general) are more reactive due to the additional nitrogen.
| [Uses]
PyAOP is a phosphonium salt used as a coupling reagent in solid-phase peptide synthesis, without undergoing side reactions with the amino terminus. PyAOP is a derivative of HOAt (H805070). |
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