| Identification | More | [Name]
4-(4-Aminophenyl)butyric acid | [CAS]
15118-60-2 | [Synonyms]
4-(4-AMINOPHENYL)BUTYRIC ACID
AKOS BB-8810
4-(4-Aminophenyl)butanoicacid
p-Aminophenylbutyricacid
4-Aminophenylbutyric Acid
4-Aminobenzenebutanoic acid
4-Amino-benzenebutanoic | [EINECS(EC#)]
628-142-4 | [Molecular Formula]
C10H13NO2 | [MDL Number]
MFCD00075052 | [Molecular Weight]
179.22 | [MOL File]
15118-60-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
121-124 °C (lit.)
121-133 °C | [Boiling point ]
363.7±17.0 °C(Predicted) | [density ]
1.177±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
4.70±0.10(Predicted) | [color ]
Light Beige to Light Brown | [InChI]
InChI=1S/C10H13NO2/c11-9-6-4-8(5-7-9)2-1-3-10(12)13/h4-7H,1-3,11H2,(H,12,13) | [InChIKey]
RBHLFWNKEWLHBP-UHFFFAOYSA-N | [SMILES]
C1(CCCC(O)=O)=CC=C(N)C=C1 | [CAS DataBase Reference]
15118-60-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [HS Code ]
2922498590 |
| Hazard Information | Back Directory | [Description]
4-(4-Aminophenyl)butyric acid (4-APB) is an important organic compound derived from butyric acid, which is used as a synthetic intermediate for pharmaceuticals or the synthesis of various compounds. It is also used in drug mechanism studies and is thought to be an agonist for certain G-protein coupled receptors and may also interact with other proteins in the signal transduction pathway. In addition, 4-(4-aminophenyl)butyric acid has been found to inhibit monoamine oxidase, which plays a role in neurotransmitter catabolism. | [Uses]
4-(4-Aminophenyl)butyric Acid is a degradation product of Chlorambucil (C325050); an alkylating agent that is used as an chemotherapy drug in the treatment of chronic lymphocytic leukemia. Chlorambucil is also used to treat non-Hodgkin''s lymphoma (NHL) and Hodgkin''s disease. |
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