| Identification | More | [Name]
Hexamethyldisilane | [CAS]
1450-14-2 | [Synonyms]
DISILANE M6
HEXAMETHYLDISILANE
HMD
(CH3)6Si2
1,1,1,2,2,2-Hexamethyldisilane
CH7280
disilane,hexamethyl-
Hecamethyldisilane
hexamethyl-disilan
hexamethyldisilane(hmd)
Permethyldisilane
trimethyl-trimethylsilyl-silane
HEXAMETHYLDISILANE WACKER QUALITY
Hexamethyldisilane, 98+%
Hexamethyldisilane,97%
2,2,3,3-Tetramethyl-2,3-disilabutane | [EINECS(EC#)]
215-911-0 | [Molecular Formula]
C6H18Si2 | [MDL Number]
MFCD00008258 | [Molecular Weight]
146.38 | [MOL File]
1450-14-2.mol |
| Chemical Properties | Back Directory | [Appearance]
Colorless clear liquid | [Melting point ]
9-12 °C (lit.) | [Boiling point ]
112-114 °C (lit.) | [density ]
0.715 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.422(lit.)
| [Fp ]
29 °F
| [storage temp. ]
Flammables area | [solubility ]
sol common organic solvents; insol H2O. | [form ]
liquid | [color ]
colorless | [Specific Gravity]
0.729 | [Water Solubility ]
Insoluble in water. Soluble in alcohol, ether and acetone. | [Hydrolytic Sensitivity]
1: no significant reaction with aqueous systems | [BRN ]
1633463 | [Stability:]
Volatile | [InChIKey]
NEXSMEBSBIABKL-UHFFFAOYSA-N | [CAS DataBase Reference]
1450-14-2(CAS DataBase Reference) | [NIST Chemistry Reference]
Disilane, hexamethyl-(1450-14-2) | [EPA Substance Registry System]
1450-14-2(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
F,Xi | [Risk Statements ]
R11:Highly Flammable.
R36/37:Irritating to eyes and respiratory system .
R43:May cause sensitization by skin contact.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S9:Keep container in a well-ventilated place .
S33:Take precautionary measures against static discharges .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S7/9:Keep container tightly closed and in a well-ventilated place . | [RIDADR ]
UN 1993 3/PG 2
| [WGK Germany ]
2
| [RTECS ]
JM9170000
| [TSCA ]
Yes | [HazardClass ]
3 | [PackingGroup ]
II | [HS Code ]
29310095 | [Toxicity]
LD50 orally in Rabbit: 2160 mg/kg LD50 dermal Rabbit 2160 mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless clear liquid | [Uses]
Hexamethyldisilane acts as a silylating reagent for allylic acetates, aryl halides and diketones. It is a source material for vapor deposition during silicon carbide growth. It is also used in electronic and semiconducter industries. | [Application]
Hexamethyldisilane is an important silane protective agent, which can synthesize sodium trimethylsilane, potassium trimethylsilane and lithium trimethylsilane.
Preparation of iodotrimethylsilane.
Used as trimethylsilane anion reagent.
silylating or reducing reagent in combination with a Pd catalyst or a nucleophile.
Replaces aromatic nitriles with TMS groups in presence of [RhCl(cod)]2.
Precursor for CVD of silicon carbide.
Brings about the homocoupling of arenesulfonyl chlorides in the presence of Pd2(dba)3.
Used as a solvent for the direct borylation of fluoroaromatics.
Reacts with alkynes to form siloles.
Undergoes the silylation of acid chlorides to give acylsilanes. | [Preparation]
Hexamethyldisilane is produced by the reaction of methyl Grignard reagent with methylchlorodisilanes. This reaction is normally conducted in the presence of an ether such as diethyl ether, ethyl propyl ether, THF and the like. | [Fire Hazard]
Hexamethyldisilazane (HMDZ) is a highly flammable liquid and vapour.
HMDZ liquid is lighter than water and may float on water, spreading material during fire fighting. Leaking material or fire runoff to sewer may create fire or explosion hazard.
HMDZ vapours are heavier than air and can accumulate to form explosive concentrations. The vapours may also spread a considerable distance to a source of ignition, and flash back towards the source.
HMDZ reacts with water to form ammonia.
HMDZ is a non-conductor and, therefore, can accumulate static electrical charges when processed, handled or dispensed. HMDZ's flash point is 52 to 53°F, closed cup, for "pure" material. | [Purification Methods]
The most likely impurity is trimethylchlorosilane (cf boiling point). Wash it with H2O, cold conc H2SO4, H2O again, then aqueous NaHCO3, dry over CaSO4 and fractionate at atmospheric pressure. [Brown & Fowles J Chem Soc 2811 1958.] A grossly impure sample (25% impurities) was purified by repeated spinning band distillation. This lowered the impurity level to 500ppm. The main impurity was identified as 1-hydroxypentamethyldisilane. [Beilstein 4 IV 4277.] |
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