| Identification | More | [Name]
Aniline hydrochloride | [CAS]
142-04-1 | [Synonyms]
Anilinechlofide
ANILINE HCL
ANILINE HYDROCHLORIDE
ANILINIUM CHLORIDE
benzenamine hydrochloride
C.I. 76001
anilinechloride
chlorhydrated’aniline
chloridanilinu
nci-c03736hydrochloride
phenylaminehydrochloride
phenylammoniumchloride
sulanilinova
usafek-442
ANILINE CHLORHYDRATE
ANILINE HYDROCHLORIDE FOR SUGAR &
ANILINE HYDROCHLORIDE, FOR SUGAR ANALYSIS
AnilineHydrochlorideForSynthesis
Aniline salt
Aniline hydrochloride, pure, 99% | [EINECS(EC#)]
205-519-8 | [Molecular Formula]
C6H8ClN | [MDL Number]
MFCD00012958 | [Molecular Weight]
129.59 | [MOL File]
142-04-1.mol |
| Chemical Properties | Back Directory | [Appearance]
Aniline is a clear, colorless, oily liquid that darkens
on exposure to light; with a characteristic amine-like
odor. | [Melting point ]
196-198 °C(lit.) | [Boiling point ]
245 °C | [density ]
1.2215 | [vapor density ]
4.46 (vs air)
| [refractive index ]
1.5330 (estimate) | [Fp ]
380 °F
| [storage temp. ]
Store below +30°C. | [solubility ]
1070g/l | [form ]
Powder | [color ]
White to pale yellow-cream | [Stability:]
Stable. Incompatible with strong oxidizing agents, strong acids. | [Water Solubility ]
1070 g/L (25 ºC) | [Sensitive ]
Hygroscopic | [Merck ]
14,659 | [BRN ]
3593823 | [CAS DataBase Reference]
142-04-1(CAS DataBase Reference) | [IARC]
2A (Vol. 127) | [NIST Chemistry Reference]
Benzenamine, hydrochloride(142-04-1) | [EPA Substance Registry System]
142-04-1(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T,N | [Risk Statements ]
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R40:Limited evidence of a carcinogenic effect.
R41:Risk of serious damage to eyes.
R43:May cause sensitization by skin contact.
R48/23/24/25:Toxic: danger of serious damage to health by prolonged exposure through inhalation, in contact with skin and if swallowed .
R50:Very Toxic to aquatic organisms.
R68:Possible risk of irreversible effects. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S27:Take off immediately all contaminated clothing .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S63:In case of accident by inhalation, remove casualty to fresh air and keep at rest. | [RIDADR ]
UN 1548 6.1/PG 3
| [WGK Germany ]
2
| [RTECS ]
CY0875000
| [F ]
3-9 | [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29214100 | [Safety Profile]
Suspected carcinogen
with experimental carcinogenic and
tumorigenic data. Poison by intraperitoneal
route. Moderately toxic by ingestion.
Experimental teratogenic effects. Human
mutation data reported. A skin and eye
irritant. Combustible when exposed to heat
or flame. When heated to decomposition or
on contact with acid or acid fumes, it emits
highly toxic fumes of aniline and chlorine
compounds. Reacts explosively with aniline at 240℃/7.6 bar. Can react vigorously with
oxidizing materials. To fight fire, use water,
CO2, water mist or spray, dry chemical. See
also ANILINE. | [Toxicity]
LD50 orally in Rabbit: 840 mg/kg |
| Hazard Information | Back Directory | [General Description]
A white to greenish colored crystalline solid. Toxic by ingestion and a skin and eye irritant. May emit toxic aniline and chloride fumes under exposure to high temperatures or flame. Used to make dyes and printing ink. | [Reactivity Profile]
ANILINE HYDROCHLORIDE(142-04-1) is incompatible with oxidizing materials. | [Air & Water Reactions]
This compound is sensitive to air and light (darkens). Soluble in water and denser than water. | [Health Hazard]
TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. | [Potential Exposure]
Aniline is widely used as an intermediate
in the synthesis of dyestuffs. It is also used in the
manufacture of rubber accelerators and antioxidants, pharmaceuticals,
marking inks; tetryl, optical whitening agents;
photographic developers; resins, varnishes, perfumes, shoe
polishes, and many organic chemicals. | [Fire Hazard]
Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form. | [First aid]
If this chemical gets into the eyes, remove any
contact lenses at once and irrigate immediately for at least
15 minutes, occasionally lifting upper and lower lids. Seek
medical attention immediately. If this chemical contacts the
skin, remove contaminated clothing and wash immediately
with soap and water. Seek medical attention immediately.
If this chemical has been inhaled, remove from exposure,
begin rescue breathing (using universal precautions, including
resuscitation mask) if breathing has stopped and CPR if
heart action has stopped. Transfer promptly to a medical
facility. When this chemical has been swallowed, get medical
attention. Give large quantities of water and induce
vomiting. Do not make an unconscious person vomit.
| [Shipping]
UN1547 Aniline, Hazard Class: 6.1; Labels: 6.1-
Poisonous materials. UN1548 Aniline hydrochloride,
Hazard Class: 6.1; Labels: 6.1-Poisonous materials. | [Incompatibilities]
May form explosive mixture with air.
Unless inhibited (usually methanol), aniline is readily able
to polymerize. Fires and explosions may result from contact
with halogens, strong acids; oxidizers, strong base organic
anhydrides; acetic anhydride, isocyanates, aldehydes,
sodium peroxide. Strong reaction with toluene diisocyanate.
Reacts with alkali metals and alkali earth metals. Attacks
some plastics, rubber and coatings; copper and copper
alloys. | [Description]
Aniline (hydrochloride) (Item No. 21963) is an analytical reference standard that is structurally categorized as a synthetic intermediate. It is used to make the imine derivative of NPP (Item No. 20528) as part of the synthesis of fentanyl (Item Nos. 14719 | ISO60197 ) and its derivatives.1 This product is intended for research and forensic applications. | [Chemical Properties]
Aniline hydrochloride, a white to greenishcrystalline solid that meltsat 198°C and boils at 245 °C;soluble in water,alcohol, and chloroform; used in making dyes and in printing. Also known as anilinechloride,anilinesalt.
| [Chemical Properties]
Aniline is a clear, colorless, oily liquid that darkens
on exposure to light; with a characteristic amine-like
odor. | [Waste Disposal]
Consult with environmental
regulatory agencies for guidance on acceptable disposal
practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing
storage, transportation, treatment, and waste disposal.
Incineration with provision for nitrogen oxides removal from
flue gases by scrubber, catalytic or thermal device. | [Uses]
Aniline hydrochloride was used in the preparation of polyaniline coated poly(styrene-co-styrene sulfonate) nanoparticles. It was used to study the induction of Nei-like DNA glycosylases (NEIL1/2)-mediated base excision repair(BER) in rat spleen and 8-oxoguanine glycosylase 1-mediated BER due to aniline exposure. It is used in printing inks, clothing marking inks, paints and paint removers. It is also used as a stove polisher and shoe polisher, as well as in the synthesis of dyes, crayons and antioxidants. | [Uses]
Intermediates, dyeing and printing, aniline black. | [Biochem/physiol Actions]
The acute toxicity of aniline involves its activation in vivo to 4-hydroxyaniline and the formation of adducts with hemoglobin. In erythrocytes, this is associated with the release of iron and the accumulation of methemoglobin and the development of hemolytic anemia and inflammation of the spleen. Tumor formation is often observed in the spleen on prolonged administration. | [Purification Methods]
Purification is as for aniline HBr above. [Beilstein 12 IV 232.] |
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