| Identification | Back Directory | [Name]
ML281 | [CAS]
1404437-62-2 | [Synonyms]
ML281
CS-2166
ML 281;ML-281
N-(4-isopropyl-2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl)thiophene-2-carboxamide
N-[2-(3,4-Dihydro-3-oxo-2-quinoxalinyl)-4-(1-methylethyl)phenyl]-2-thiophenecarboxamide
2-Thiophenecarboxamide, N-[2-(3,4-dihydro-3-oxo-2-quinoxalinyl)-4-(1-methylethyl)phenyl]- | [Molecular Formula]
C22H19N3O2S | [MDL Number]
MFCD25976601 | [MOL File]
1404437-62-2.mol | [Molecular Weight]
389.47 |
| Chemical Properties | Back Directory | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
DMF: 33 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml; DMSO: 20 mg/ml | [form ]
A crystalline solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
ML 281 is a potent and selective quinoxalinone-based inhibitor of STK33 effectively targeting KRAS-dependent cancers. | [Definition]
ChEBI: N-[2-(3-oxo-4H-quinoxalin-2-yl)-4-propan-2-ylphenyl]-2-thiophenecarboxamide is an aromatic amide. | [storage]
Store at +4°C |
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