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ChemicalBook--->CAS DataBase List--->1366234-01-6

1366234-01-6

1366234-01-6 Structure

1366234-01-6 Structure
IdentificationBack Directory
[Name]

GSK503A)
[CAS]

1366234-01-6
[Synonyms]

GSK503A)
GSK 2833503A (GSK2833503A
[Molecular Formula]

C18H21ClFN3OS
[MOL File]

1366234-01-6.mol
[Molecular Weight]

381.9
Chemical PropertiesBack Directory
[solubility ]

Soluble to 100 mM in DMSO and to 20 mM in ethanol
Hazard InformationBack Directory
[Description]

GSK 2833503A is a potent, and selective inhibitor of TRPC3/6 channels with IC50 of 4 nM/5 nM, respectively. It dispalys >100-fold selectivity over other calcium-permeable channels. It has 100-fold greater potency for TRPC3 compared with Pyr3. GSK 2833503A (dose-dependent) blocks cell hypertrophy signaling triggered by angiotensin II or endothelin-1 in HEK293T cells as well as in neonatal and adult cardiac myocytes.
[storage]

Store at -20°C
1366234-01-6 suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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