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ChemicalBook--->CAS DataBase List--->1356565-46-2

1356565-46-2

1356565-46-2 Structure

1356565-46-2 Structure
IdentificationBack Directory
[Name]

N-DESMETHYL IMATINIB
[CAS]

1356565-46-2
[Synonyms]

N-DESMETHYL GLEEVEC
N-DESMETHYL IMATINIB
Imatinib Impurity 53
N-DESMETHYL IMATINIB USP/EP/BP
N-DESMETHYL IMATINIB impurity B
Imatinib desmethyl (as formate)
N-4-((4-Methylpiperazin-1-yl)methyl)benzaldehyde
Benzamide, N-[2-methyl-5-[[4-[(4-methyl-1-piperazinyl)methyl]benzoyl]amino]phenyl]-4-[(4-methyl-1-piperazinyl)methyl]-N-[4-(3-pyridinyl)-2-pyrimidinyl]-
[Molecular Formula]

C42H47N9O2
[MDL Number]

MFCD07369291
[MOL File]

1356565-46-2.mol
[Molecular Weight]

709.88
Chemical PropertiesBack Directory
[Melting point ]

180 - 190°C
[density ]

1.248±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[solubility ]

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

13.20±0.70(Predicted)
[color ]

Off-White to Light Yellow
Hazard InformationBack Directory
[Uses]

Gleevec N-4-((4-Methylpiperazin-1-yl)methyl)benzaldehyde is an impurity of Gleevec (G407000), a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL).
[Uses]

N-Desmethyl Imatinib (Imatinib EP Impurity C) is a metabolite of Gleevec, a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product.
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