| Identification | Back Directory | [Name]
(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL | [CAS]
134234-12-1 | [Synonyms]
CP-101
CP 98113
CP 101606
1-((1S,2S)
Traxoprodil
propan-2-yl)
(+)-CP 101,606
CP-101,606 >=98% (HPLC)
Traxoprodil(CP-101,606)
CP-101;606;CP 101606;CP101606
-1-Hydroxy-1-(4-hydroxyphenyl)
(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL
1-((1S,2S)-1-Hydroxy-1-(4-hydroxyphenyl)propan-2-yl)-4-phenylpiperidin-4-ol
1-[(1S,2S)-2-Hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]-4-phenylpiperidin-4-ol
(1s,2s)-1-[4-[ hydroxylphenyl]- 2- ( 4-hydroxy-4-pheny1piperidino)-1- propanol
1-Piperidineethanol, 4-hydroxy-α-(4-hydroxyphenyl)-β-methyl-4-phenyl-, (αS,βS)-
[S-(R*,R*)]-4-Hydroxy-alpha-(4-hydroxyphenyl)-beta-methyl-4-phenyl-1-piperidineethanol | [Molecular Formula]
C20H25NO3 | [MDL Number]
MFCD00926469 | [MOL File]
134234-12-1.mol | [Molecular Weight]
327.42 |
| Chemical Properties | Back Directory | [Boiling point ]
534.4±50.0 °C(Predicted) | [density ]
1.228 | [storage temp. ]
2-8°C | [solubility ]
DMSO: ≥35mg/mL | [form ]
powder | [pka]
9.99±0.26(Predicted) | [color ]
white to tan | [optical activity]
[α]/D +50 to +60° (c=1, MeOH) |
| Hazard Information | Back Directory | [Uses]
CP-101,606 has been used as a N-methyl-D-aspartate (NMDA)?receptor antagonist to study its role in recovery of spinal cord injuries. | [Uses]
Traxoprodil (CP101,606) is a potent and selective NMDA antagonist and protect hippocampal neurons with an IC50 of 10 nM. | [Brand name]
Traxoprodil is INN. | [General Description]
CP-101,606 (Traxoprodil) is a substituted 4-phenylpiperidine and is localized in the fore brain neurons. | [Biochem/physiol Actions]
Traxoprodil (CP-101,606) is a potent noncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptors, selective for the NR2B subunit. It has been shown to be neuroprotective in animal models of brain injury and stroke. | [storage]
Store at -20°C |
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