| Identification | Back Directory | [Name]
AM-8508 | [CAS]
1338483-67-2 | [Synonyms]
AM-8508
(S)-4-AMINO-6-((1-(6-FLUORO-1-(PYRIDIN-3-YL)-1H-BENZO[D]IMIDAZOL-2-YL)ETHYL)AMINO)PYRIMIDINE-5-CARBONITRILE | [Molecular Formula]
C19H15FN8 | [MDL Number]
MFCD30471147 | [MOL File]
1338483-67-2.mol | [Molecular Weight]
374.37 |
| Hazard Information | Back Directory | [Description]
AM-8508 is a potent and selective PI3Kδ inhibitor. AM-8508 showed good cellular potency (in vitro pAKT IC50 = 4.6 nM ). AM-8505 xhibited excellent HWB potency (HWB (pAKT) IC50 = 2.7 nM). AM-8508 inhibit KLH-specific antibodies in animal models, signifying its potential for the treatment of human inflammatory diseases. PI3Kα and PI3Kβ are ubiquitously expressed and play a role in cell growth, division, and survival. |
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| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
| Company Name: |
AstaTech, Inc
|
| Tel: |
(215) 785 3197 |
| Website: |
www.astatechinc.com |
|