| Identification | Back Directory | [Name]
AM-9635 | [CAS]
1338483-10-5 | [Synonyms]
AM-9635
5-Pyrimidinecarbonitrile, 4-amino-6-[[(1S)-1-[6-fluoro-1-(5-fluoro-3-pyridinyl)-1H-benzimidazol-2-yl]ethyl]amino]-
(S)-4-AMINO-6-((1-(6-FLUORO-1-(5-FLUOROPYRIDIN-3-YL)-1H-BENZO[D]IMIDAZOL-2-YL)ETHYL)AMINO)PYRIMIDINE-5-CARBONITRILE | [Molecular Formula]
C19H14F2N8 | [MDL Number]
MFCD30471148 | [MOL File]
1338483-10-5.mol | [Molecular Weight]
392.36 |
| Hazard Information | Back Directory | [Description]
AM-9635 is a potent and selective PI3Kδ inhibitor. AM-9635 showes good cellular potency (in vitro pAKT IC50 = 4.2 nM ). AM-96352 inhibits KLH-specific IgG and IgM in a dosedependent manner AM-9635 is well tolerated at all doses and exhibits significantly reduced IgG and IgM specific antibodies . PI3Kα and PI3Kβ are ubiquitously expressed and play a role in cell growth, division, and survival. |
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| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
| Company Name: |
AstaTech, Inc
|
| Tel: |
(215) 785 3197 |
| Website: |
www.astatechinc.com |
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