| Identification | More | [Name]
Hydroxyapatite | [CAS]
1306-06-5 | [Synonyms]
ALTERNATING COPOLY: BETA-GLUCURONIC ACID-[1->5]-BETA-N-ACETYL GLUCOSAMINE-[1->4]
APATITE HAP, MONOCLINIC
BEEF BONE POWDER
BONE ASH
CALCIUM HYDROXIDE PHOSPHATE
CALCIUM HYDROXYAPATITE
CALCIUM PHOSPHATE
CALCIUM PHOSPHATE HYDROXIDE
CALCIUM PHOSPHATE TRIBASIC
COPOLY(BETA-GLUCURONIC ACID-[1->3]-BETA-N-ACETYLGLUCOSAMINE-[1->4]
DURAPATITE
HA
HA, BOVINE
HYALURONIC ACID
HYALURONIC ACID, BOVINE
HYALURONIC ACID HUMAN
HYDROXYAPATITE
HYDROXYLAPATITE
HYDROXYLAPATITE CERAMIC
TCP | [EINECS(EC#)]
232-678-0 | [Molecular Formula]
Ca5HO13P3 | [MDL Number]
MFCD00010904 | [Molecular Weight]
502.31 | [MOL File]
1306-06-5.mol |
| Chemical Properties | Back Directory | [Definition]
The major constituent of bone and tooth mineral. It is finely divided, crystalline, nonstoichiometric material rich in surface ions (carbonate, magnesium, citrate), which are readily replaced by fluoride ion, thus affording protection to the teeth. | [Appearance]
white powder | [Melting point ]
1100 °C(lit.)
| [density ]
3.076 g/cm3(Temp: 18 °C) | [storage temp. ]
−20°C
| [solubility ]
H2O: 0.3 mg/mL, clear, colorless
| [form ]
solid
| [color ]
White | [Water Solubility ]
insoluble H2O [MER06] | [Merck ]
13,3500 | [CAS DataBase Reference]
1306-06-5(CAS DataBase Reference) | [EPA Substance Registry System]
1306-06-5(EPA Substance) |
| Hazard Information | Back Directory | [Chemical Properties]
white powder | [Uses]
Prosthetic aid (artificial bone and teeth). | [Brand name]
Alveograf (Sterling Winthrop); Periograf (Sterling Winthrop). | [Description]
Calcium hydroxyapatite has a unique structure in
that it is conductive along the hydroxide channels.
OH- ions lie at (1/4/,1/4,1/4) and (3/4/,3/4,3/4) on
the c-axis and charge-carrying protons are responsible
for the observed conductivities in M10(PO4)6(OH)2. The
H+ migration between the electroattractive ion (O2)
to give molecular H2O in matrix channels carries charge
and the resulting conductivity.
The unit cell consists of two triangular prismatic subcells
forming a rhombic prism with vertical sides. There
are two horizontal mirror planes at the OH levels of 1/4
and 3/4 of the c-axis. In addition, there is a center of
inversion exactly in the center of each vertical face of
each subcell. | [Occurrence]
Occurs in nature as the minerals: oxydapatit, voelicherite, whitlockite. | [Preparation]
The technical product is also known as “bone ash.” Commercial preparation from phosphate rock. | [General Description]
Bone and tooth implant materials have been prepared from polycrystalline hydroxyapatite. The compressive, flexural, torsional and dynamic torsional strengths of polycrystalline hydroxyapatite were investigated. Electrophoretic deposition of hydroxyapatite on to flat titanium plate material has been studied. | [Flammability and Explosibility]
Notclassified | [Pharmaceutical Applications]
Modified hydroxylapatite, also frequently called hydroxyapatite and better known as bone mineral, makes
up ～50% of our bones. Hydroxylapatite is a natural form of the mineral calcium apatite, whose formula is usually denoted as Ca10(PO4)6(OH)2. Modifications of hydroxylapatite can also be found in the teeth, and a
chemically identical substance is often used as filler for replacement of bones, and so on. Nevertheless, despite
similar or identical chemical compositions, the response of the body to these compounds can be quite different. | [storage]
Store at -20°C |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
MY8434000
| [F ]
3-10 | [TSCA ]
Yes | [HS Code ]
28352600 | [Hazardous Substances Data]
1306-06-5(Hazardous Substances Data) |
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