| Identification | Back Directory | [Name]
Sparstolonin B | [CAS]
1259330-61-4 | [Synonyms]
Sparstolonin B
Sparstolonin B >=98% (HPLC)
3H-Pyrano[3,4,5-kl]xanthen-3-one, 4,10-dihydroxy- | [Molecular Formula]
C15H8O5 | [MDL Number]
MFCD28139298 | [MOL File]
1259330-61-4.mol | [Molecular Weight]
268.22 |
| Hazard Information | Back Directory | [Biochem/physiol Actions]
Sparstolonin B (SsnB) is a polyphenol. It has a structural features similar to xanthone and isocoumarin. SsnB exerts anti-inflammatory properties on mouse and human macrophages. SsnB can significantly reduce hypoxia–reoxygenation-induced inflammation of cardiomyocytes by blocking extracellular signal-regulated protein kinase (ERK1/2) and c-jun N-terminal kinases (JNK) signaling pathways. Thus, SsnB acts as a potent therapeutic for the treatment of myocardial ischemia–reperfusion (MIR) injury. |
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Sigma-Aldrich
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Energy Chemical
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http://www.energy-chemical.com |
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