| Identification | More | [Name]
Fenazaquin | [CAS]
120928-09-8 | [Synonyms]
FENAZAQUIN
MAGISTER
4-((4-(1,1-dimethylethyl)phenyl)ethoxy)-quinazolin
4-((4-(1,1-dimethylethyl)phenyl)ethoxy)quinazoline
4-(2-(4-(1,1-dimethylethyl)phenyl)ethoxy)quinazoline
4-tert-butylphenethylquinazolin-4-ylether
el436
FENAZAQUIN PESTANAL, 100 MG
FENAZAQUIN ANALYTICAL STANDARD
Quinazoline, 4-2-4-(1,1-dimethylethyl)phenylethoxy-
4-tert-Butyl phenylethyl quinazolin-4-yl ether | [EINECS(EC#)]
410-580-0 | [Molecular Formula]
C20H22N2O | [MDL Number]
MFCD01656049 | [Molecular Weight]
306.4 | [MOL File]
120928-09-8.mol |
| Chemical Properties | Back Directory | [Melting point ]
70-71° (Dreikorn); mp 77.5-80.0° (Gambie) | [Boiling point ]
447.01°C (rough estimate) | [density ]
1.0970 (rough estimate) | [vapor pressure ]
3.4 x l0-6 Pa (25 °C) | [refractive index ]
1.5700 (estimate) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly) | [form ]
neat | [pka]
2.88±0.30(Predicted) | [Water Solubility ]
0.102 mg l-1 (20 °C, pH 7) | [BRN ]
8331263 | [LogP]
5.510 | [CAS DataBase Reference]
120928-09-8(CAS DataBase Reference) | [EPA Substance Registry System]
120928-09-8(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T,N | [Risk Statements ]
R20:Harmful by inhalation.
R25:Toxic if swallowed.
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S37:Wear suitable gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S60:This material and/or its container must be disposed of as hazardous waste .
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [RIDADR ]
UN 2811 6.1/PG 3 | [WGK Germany ]
3 | [RTECS ]
VA1382000 | [Hazardous Substances Data]
120928-09-8(Hazardous Substances Data) | [Toxicity]
LD50 orally in rats, mice (mg/kg): 134, 1480; dermally in rabbits (mg/kg): >5000; LC50 (96 hr) in bluegill, trout (mg/l): 34.1, 3.8 (Longhurst) |
| Hazard Information | Back Directory | [Uses]
Acaricide and insecticide. | [Uses]
Fenazaquin is a non-systemic acaricide/insecticide used widely in controlling mites and other related pests in fruits, vegetables and tea. | [Uses]
Fenazaquin is an acaricide mainly used for control of mites
(Eutetranychus, Panonychus and Tetranychus spp.) on pome and citrus
fruits and glasshouse-grown ornamental plants. | [Definition]
ChEBI: Fenazaquin is a member of quinazolines. It has a role as an acaricide and a mitochondrial NADH:ubiquinone reductase inhibitor. | [Metabolic pathway]
Fenazaquin is a lipophilic compound and hence is immobile in soils and is
not translocated in plants. The main pathways of metabolism involve
cleavage of the bridging group between the quinazoline and phenyl rings,
oxidation of the tert-butyl sustituent and of the heterocyclic portion of the
quinazoline ring and cleavage of that ring. Most of the information is
taken from a pamphlet produced by the manufacturer of the compound in
which full experimental details were not given (DowElanco, 1993). | [Degradation]
Fenazaquin is hydrolysed under acidic conditions but the rate is slow
under neutral and alkaline conditions. Half-lives were 8,442 and 584 days
(22 °C) at pH values of 5, 7 and 9, respectively. Hydrolysis occurs by
cleavage of the ether linkage to form quinazolin-2-ol (2) and an alcohol
(3) as shown in Scheme 1. The major route of degradation in aquatic
environments is by photolysis, the main products (2 and 3) being formed
by cleavage of the ether lmkage and include the alkene (4) (DowElanco,
1993). |
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