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ChemicalBook--->CAS DataBase List--->113443-70-2

113443-70-2

113443-70-2 Structure

113443-70-2 Structure
IdentificationBack Directory
[Name]

RHEIN-8-GLUCOSIDE
[CAS]

113443-70-2
[Synonyms]

Glucorhein
Rhein-8-glucoside calcium
Rhein-8-O-β-D-glucopyranoside
Rhein-8-glucoside calcium salt
Rhein-8-O-beta-D-glucopyranoside
Rhein-8-O-β-D-glucopyranoside(Rhein-8-glucoside calcium )
(-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside
2-Anthracenecarboxylicacid, 8-b-D-glucopyranosyl-9,10-dihydro-4,5-dihydroxy-9,10-dioxo-,calciuM salt (1:1)
calcium,3-carboxy-9,10-dioxo-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]anthracene-1,8-diolate
[Molecular Formula]

C21H20CaO11
[MOL File]

113443-70-2.mol
[Molecular Weight]

488.46
Chemical PropertiesBack Directory
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

powder
[color ]

Yellow
Hazard InformationBack Directory
[Chemical Properties]

Yellow crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the rhizome of rhubarb.
[Uses]

Rhein-8-O-glucoside extracted from rhubarb has anti-tumor, antibacterial and immunosuppressive effects.

[Definition]

ChEBI:Glucorhein is a member of anthracenes.
[Biological Activity]

Rhein-8-glucoside calcium, an anthraquinone compound isolated from the EtOH extract of Saussurea lappa root. It is a hPTP1B inhibitor with IC50 of 11.5 μM. It has antibacterial properties.
[target]

IC50: 11.5 μM (hPTP1B)

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