| Identification | More | [Name]
tert-Butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate | [CAS]
112741-50-1 | [Synonyms]
(5R,6S)-4-TERT-BUTOXYCARBONYL-5,6-DIPHENYLMORPHOLIN-2-ONE
N-BOC(2S, 3R)-(+)-6-OXO-2,3-DIPHENYL-4-MORPHOLINE CARBOXYLATE
N-TERT-BUTOXYCARBONYL-(2S,3R)-(+)-6-OXO-2,3-DIPHENYL-4-MORPHOLINE-CARBOXYLATE
TERT-BUTYL (2S,3R)-(+)-6-OXO-2,3-DIPHENYL-4-MORPHOLINECARBOXYLATE
tert-butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morph
TERT-BUTYL (2S,3R)-(+)-6-OXO-2,3-DIPHENY L-4-MORPHOLINECARBOXYLATE, 99% (99% EE)
(2S,3R)-tert-Butyl 6-oxo-2,3-diphenylmorpholine-4-carboxylate
(5S,6R)-4-tert-Butoxycarbonyl-5,6-diphenylmorpholin-2-one
(2S,3R)-6-Oxo-2,3-diphenyl-morpholine-4-carboxylic acid tert-butyl ester
(5R,6S)-N-Boc-5,6-diphenyl-2-morpholinone | [EINECS(EC#)]
627-150-5 | [Molecular Formula]
C21H23NO4 | [MDL Number]
MFCD00074953 | [Molecular Weight]
353.41 | [MOL File]
112741-50-1.mol |
| Chemical Properties | Back Directory | [Melting point ]
206 °C (dec.)(lit.) | [alpha ]
86 º (c=5.5 in methylene chloride) | [Boiling point ]
509.6±50.0 °C(Predicted) | [density ]
1.175±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [pka]
-3.28±0.60(Predicted) | [optical activity]
[α]20/D +86°, c = 5.5 in methylene chloride | [InChIKey]
MRUKRSQUUNYOFK-MOPGFXCFSA-N | [CAS DataBase Reference]
112741-50-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
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| Hazard Information | Back Directory | [Uses]
(2S,3R)-(+)-N-Boc-6-oxo-2,3-diphenylmorpholine (Williams chiral auxiliary) can be used as a reactant:
- In the asymmetric synthesis of cylindrospermopsin and related alkaloids via an intramolecular 1,3-dipolar cycloaddition reaction.
- To synthesize boc-3-(1-methylcyclopropyl)-D-alanine, which is used as an intermediate to prepare 4-fluoroproline-based analogs as potent tripeptide thrombin inhibitors.
- In the total synthesis of potent hepatotoxic alkaloid 7-epicylindrospermopsin by intramolecular 1,3-dipolar cycloaddition and nitroaldol reaction.
- To prepare differentially functionalized diaminoglutamic acids via radical reaction of selenide with methyl 2-acetamidoacrylate.
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