Identification | Back Directory | [Name]
Englerin A | [CAS]
1094250-15-3 | [Synonyms]
Englerin A (-)-ENGLERIN A (?)-Englerin A Englerin A high purity (1S,2R,5R,6R,7S,8R,10R)-10-(Glycoloyloxy)-8-isopropyl-1,5-dimethyl-11-oxatricyclo[6.2.1.02,6]undec-7-yl(2E)-3-phenylacrylate 2-Propenoic acid, 3-phenyl-, (1R,3aR,4S,5R,7R,8S,8aR)-decahydro-5-[(2-hydroxyacetyl)oxy]-1,4-dimethyl-7-(1-methylethyl)-4,7-epoxyazulen-8-yl ester, (2E)- | [Molecular Formula]
C26H34O6 | [MDL Number]
MFCD32068367 | [MOL File]
1094250-15-3.mol | [Molecular Weight]
442.54 |
Chemical Properties | Back Directory | [Boiling point ]
550.3±50.0 °C(Predicted) | [density ]
1.20±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
12.88±0.10(Predicted) | [color ]
White to light yellow |
Hazard Information | Back Directory | [Uses]
Englerin A is a selective inhibitor of renal cancer cell growth. | [Definition]
ChEBI: Englerin A is a guaiane sesquiterpenoid that is isolated from the bark of Phyllanthus engleri, a plant native to Tanzania and Zimbabwe. It acts as a potent and specific inhibitor of renal cancer cell growth. It has a role as a metabolite and an antineoplastic agent. It is a guaiane sesquiterpenoid, a cinnamate ester and a glycolate ester. |
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