| Identification | Back Directory | [Name]
Methyl 4-(4-oxobutyl)benzoate | [CAS]
106200-41-3 | [Synonyms]
Pemetrexed Impurity 41
Pemetrexed Impurity 52
Pemetrexed Related Impurity 5
Methyl 4-(4-oxobutyl)benzoate
4-(4-Oxobutyl)benzoic acid methyl ester
4-(4-CARBOMETHOXYPHENYL)BUTANAL(WXG01250)
Benzoic acid, 4-(4-oxobutyl)-, methyl ester | [EINECS(EC#)]
1592732-453-0 | [Molecular Formula]
C12H14O3 | [MOL File]
106200-41-3.mol | [Molecular Weight]
206.24 |
| Chemical Properties | Back Directory | [Melting point ]
76.5-78 °C(Solv: ethyl ether (60-29-7)) | [Boiling point ]
131 °C(Press: <1 Torr) | [density ]
1.082±0.06 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, Refrigerator, under inert atmosphere | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Oil | [color ]
Clear Colourless | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
4-(4-Oxobutyl)benzoic Acid Methyl Ester is used as a reagent in the preparation of Pemetrexed (P219500) and furoxanoxyalkyl esters of Pemetrexed as antifolates and nitric oxide donors for use as anticancer agents. | [Synthesis Reference(s)]
Journal of Heterocyclic Chemistry, 23, p. 1, 1986 DOI: 10.1002/jhet.5570230101 |
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