| Identification | More | [Name]
4-BROMOTHIOPHENOL | [CAS]
106-53-6 | [Synonyms]
4-BROMOBENZENETHIOL
4-BROMOTHIOPHENOL
P-BROMOBENZENETHIOL
P-BROMOTHIOPHENOL
4-bromo-benzenethio
Benzenethiol, p-bromo-
p-Bromophenyl thiol
4-Bromothiophenol,98%
4-Bromothiophenol 97%
4-bromobenzene-1-thiol | [EINECS(EC#)]
203-407-3 | [Molecular Formula]
C6H5BrS | [MDL Number]
MFCD00004845 | [Molecular Weight]
189.07 | [MOL File]
106-53-6.mol |
| Chemical Properties | Back Directory | [Appearance]
WHITE TO BEIGE CRYSTALS OR CRYSTALLINE POWDER | [Melting point ]
73-76 °C (lit.) | [Boiling point ]
239 °C (lit.) | [density ]
1.5260 | [Fp ]
239°C | [storage temp. ]
Refrigerator | [Water Solubility ]
Slightly soluble in water | [form ]
Crystals or Crystalline Powder | [pka]
6.08±0.10(Predicted) | [color ]
White to beige | [Sensitive ]
Air Sensitive | [Detection Methods]
HPLC,GC,NMR | [BRN ]
507031 | [InChIKey]
FTBCOQFMQSTCQQ-UHFFFAOYSA-N | [CAS DataBase Reference]
106-53-6(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzenethiol, 4-bromo-(106-53-6) | [EPA Substance Registry System]
106-53-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,T,C | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
2923 | [WGK Germany ]
3
| [F ]
10-13-23 | [Hazard Note ]
Irritant | [TSCA ]
T | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29309090 |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
4-Bromobenzenesulfonyl chloride-->Phosphorus-->iodine-->4,4'-Dibromodiphenyl disulfide-->BIS(4-BROMOPHENYL)DISULFIDE | [Preparation Products]
4H-AMINO-6-BROMO-2,3-DIHYDROTHIOCHROMEN-1,1-DIOXIDE-->1-BENZOTHIOPHENE-5-CARBOXYLIC ACID-->4-Hydroxy-6-bromo-2,3-dihydrothiochromen-1,1-dioxide-->2-(1-BENZOTHIOPHEN-5-YL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE-->1-BROMO-4-(METHYLSULPHONYL)-2-NITROBENZENE-->(5-BROMO-3-BENZO[B]THIENYL)METHANOL-->1-BENZOTHIOPHENE-5-CARBONITRILE-->5-BROMOBENZO[B]THIOPHENE-3-CARBOXYLIC ACID-->BENZO[B]THIOPHEN-5-YL-5-BORONIC ACID-->6-bromo-2,3-dihydrothiochromen-1,1-dioxide-4-one-->5-Bromobenzo[c]thiophene-->1-(5-BROMO-1-BENZOTHIEN-3-YL)ETHANONE-->4-BROMOBENZENESULFONIC ACID MONOHYDRATE-->6-bromo-2,3-dihydrothiochromen-4-one-->4-Mercaptophenylboronic acid-->4-(ETHYLTHIO)BENZENEBORONIC ACID-->4-(Methylthio)phenylboronic acid-->4-(TRIFLUOROMETHYLTHIO)BROMOBENZENE-->1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4R)-rel--->4-[(4-BROMOPHENYL)SULFONYL]PIPERIDINE |
| Hazard Information | Back Directory | [Chemical Properties]
WHITE TO BEIGE CRYSTALS OR CRYSTALLINE POWDER | [Uses]
4-Bromothiophenol is a reagent used in the synthesis of indolyl-3-ehtanone-α-thioethers which act as non-toxic antimalrial agents. These compounds show anti-malarial activity, with no toxicity to a HeLa cell line. | [Application]
4-Bromobenzenethiol can undergo Suzuki-Miyaura reaction on palladium nanoparticles, whereas on gold nanoparticles it only undergoes a self-coupling reaction, and these two processes are known as hot carrier-induced processes. | [Synthesis]
4-Bromothiophenol can be synthesized via the reduction of 4-bromo-benzenesulfonyl chloride by red phosphorus and iodine in an acidic solution. Hydrogenation of 4,4'-dibromodiphenyl disulfide also produces 4-bromothiophenol. |
|
|