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ChemicalBook--->CAS DataBase List--->106-52-5

106-52-5

106-52-5 Structure

106-52-5 Structure
IdentificationMore
[Name]

N-Methyl-4-piperidinol
[CAS]

106-52-5
[Synonyms]

1-HYDROXY-4-METHYLPIPERIDINE
1-METHYL-4-HYDROXYPIPERIDINE
1-METHYL-4-PIPERIDINOL
1-METHYL-4-PIPERIDINOL HCL
1-METHYL-4-PIPERIDINOLHYDROCHOLORIDE
4-HYDROXY-1-METHYLPIPERIDINE
4-HYDROXY-N-METHYLPIPERIDINE
NM4PPOL
N-METHYL-4-HYDROXY PIPERIDINE
N-METHYL-4-PIPERIDINOL
TIMTEC-BB SBB004301
1-methyl-4-piperidino
1-Methylpiperidinol-(4)
4-Piperidinol, 1-methyl-
N-Methylpiperidol
1-methylpiperidin-4-ol
N-Methyl-4-hydroxy
4-Hydroxy-1-methylpiperidine 98%
4-Hydroxy-l-methylpiperidine
1-Methyl-4-piperidinol, 4-Hydroxy-1-methylpiperidine
[EINECS(EC#)]

203-406-8
[Molecular Formula]

C6H13NO
[MDL Number]

MFCD08061316
[Molecular Weight]

115.17
[MOL File]

106-52-5.mol
Chemical PropertiesBack Directory
[Appearance]

clear colorless to yellowish liquid after melting
[Melting point ]

29-31 °C(lit.)
[Boiling point ]

200 °C(lit.)
[density ]

0.98 g/mL at 20 °C(lit.)
[vapor pressure ]

8.13-11Pa at 25℃
[refractive index ]

n20/D 1.479
[Fp ]

190 °F
[storage temp. ]

2-8°C
[form ]

Liquid After Melting
[pka]

14.87±0.20(Predicted)
[color ]

Clear colorless to brown
[Water Solubility ]

MISCIBLE
[Sensitive ]

Hygroscopic
[Detection Methods]

GC,NMR
[BRN ]

103024
[CAS DataBase Reference]

106-52-5(CAS DataBase Reference)
[NIST Chemistry Reference]

4-Hydroxy-N-methylpiperidine(106-52-5)
[Storage Precautions]

Moisture sensitive;Air sensitive
[EPA Substance Registry System]

106-52-5(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

Xi,C
[Risk Statements ]

R37/38:Irritating to respiratory system and skin .
R41:Risk of serious damage to eyes.
R36/37/38:Irritating to eyes, respiratory system and skin .
R34:Causes burns.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S27:Take off immediately all contaminated clothing .
[WGK Germany ]

3
[Hazard Note ]

Irritant
[TSCA ]

Yes
[HS Code ]

29333999
Raw materials And Preparation ProductsBack Directory
[Raw materials]

1-Methyl-4-piperidone-->1-methyl-4-phenylpiperidin-4-ol-->N,N-DI-(BETA-CARBOETHOXYETHYL)METHYLAMINE-->1-Methyl-4(1H)-pyridinone-->1-Methyl-4-oxopiperidin-3-carboxylic acid ethyl ester-->N-(1-METHYLPIPERIDIN-4-YL)ANILINE-->3-HYDROXYGLUTARONITRILE-->1-Methyl-4-piperidinol hydrochloride-->Aniline-->4-Hydroxypiperidine-->Formaldehyde-->N-Methyl-2-pyrrolidone-->Benzene
[Preparation Products]

4-(1-METHYLPIPERIDIN-4-YLOXY)-3,5-DICHLOROBENZENAMINE-->2-chloro-6-(1-methylpiperidin-4-yloxy)pyridin-4-amine-->1-methylpiperidin-4-yl 4-iodobenzoate-->4-Iodo-1-Methyl-piperidine-->6-[(1-methylpiperidin-4-yl)oxy]pyridin-3-amine
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

1-Methyl-4-piperidinol(106-52-5).msds
Hazard InformationBack Directory
[Chemical Properties]

clear colorless to yellowish liquid after melting
[Uses]

Reactant for:• ;Optimization of Novobiocin scaffold to product antitumor agents1• ;Substitution about the rigidifying ring for histamine H4 receptor antagonist synthesis2Reactant for synthesis of:• ;CaMKII inhibitors3• ;VEGFR and FGFR kinase inhibitors4• ;Phosphoinositide-3-kinase inhibitors5• ;Protein lysine methyltransferase G9a inhibitors6
[Flammability and Explosibility]

Notclassified
Spectrum DetailBack Directory
[Spectrum Detail]

N-Methyl-4-piperidinol(106-52-5)MS
N-Methyl-4-piperidinol(106-52-5)1HNMR
N-Methyl-4-piperidinol(106-52-5)13CNMR
N-Methyl-4-piperidinol(106-52-5)IR1
N-Methyl-4-piperidinol(106-52-5)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

4-Hydroxy-N-methylpiperidine, 98%(106-52-5)
[Alfa Aesar]

4-Hydroxy-1-methylpiperidine, 98%(106-52-5)
[Sigma Aldrich]

106-52-5(sigmaaldrich)
[TCI AMERICA]

4-Hydroxy-1-methylpiperidine,>97.0%(GC)(106-52-5)
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