Identification | More | [Name]
N-METHYLISATOIC ANHYDRIDE | [CAS]
10328-92-4 | [Synonyms]
AKOS 226 MIA N-METHYLISATOIC ANHYDRIDE TIMTEC-BB SBB000196 1-Methyl-2H-3,1-benzoxazine-2,4(1H)-dione 2H-3,1-Benzoxazine-2,4(1H)-dione, 1-methyl- 4(1h)-dione,1-methyl-2h-1-benzoxazine-2 N-Methyl ia n-methylia N-Methyl-N-carboxyanthranilic anhydride N-METHYLISATOIC ANHYDRIDE, TECH., 90% N-Methylisatoicanhydride,tech.,90% 1-methyl-1H-benzo[d][1,3]oxazine-2,4-dione 1-Methyl-1,2-dihydro-4H-3,1-benzoxazine-2,4-dione 1-Methyl-1H-3,1-benzoxazine-2,4-dione 1-Methyl-4H-3,1-benzoxazine-2(1H),4-dione | [EINECS(EC#)]
233-714-8 | [Molecular Formula]
C9H7NO3 | [MDL Number]
MFCD00006815 | [Molecular Weight]
177.16 | [MOL File]
10328-92-4.mol |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
DM3140000
| [TSCA ]
Yes | [HS Code ]
2934.99.4400 |
Hazard Information | Back Directory | [Chemical Properties]
brownish chunks | [Uses]
N-Methylisatoic anhydride is a 2'-OH selective acylation agent of RNAs, and is widely used for resolving secondary RNA structures using the SHAPE (Selective 2'-Hydroxyl Acylation Analyzed by Primer Extension) technology. | [Application]
N-Methylisatoic anhydride was first condensed with ethanolamine to give N-(2-hydroxyethyl)-2-methylaminobenzamide. Cyclization of the latter with ethyl pyruvate gave quinazoline derivatives which, upon hydrolysis and dehydrative cyclization with l-methyl-2-chloropyridinium iodide, afforded the l,4-oxazines[3,4-]quinazoline. | [Definition]
ChEBI: A 3,1-benzoxazin-1,4-dione having an N-methyl substituent. | [storage]
Store at -20°C |
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