| Identification | More | [Name]
1-PHENYL-2-THIOUREA | [CAS]
103-85-5 | [Synonyms]
1-PHENYL-2-THIOUREA
1-PHENYLTHIOUREA
AKOS B029691
AKOS BBS-00000800
N-PHENYLTHIOUREA
PHENYL-2-THIOUREA
PHENYLTHIOCARBAMIDE
PHENYLTHIOUREA
PTC
1-phenyl-2-thio-ure
alpha-Phenylthiourea
Fenylthiomocovina
NCI-C02017
phenyl-thioure
phenylthiourea0
Rcra waste number P093
rcrawastenumberp093
U 6324
u6324
Urea, 1-phenyl-2-thio- | [EINECS(EC#)]
203-151-2 | [Molecular Formula]
C7H8N2S | [MDL Number]
MFCD00004933 | [Molecular Weight]
152.22 | [MOL File]
103-85-5.mol |
| Chemical Properties | Back Directory | [Appearance]
N-phenylthiourea is a colorless crystalline solid. | [Melting point ]
145-150 °C(lit.)
| [Boiling point ]
266.7±23.0 °C(Predicted) | [density ]
1.3 | [refractive index ]
1.5500 (estimate) | [storage temp. ]
Poison room | [solubility ]
Soluble in alcohol | [form ]
Crystalline Powder | [pka]
13.12±0.70(Predicted) | [color ]
Off-white to beige | [Stability:]
Stable. Incompatible with strong acids, strong oxidizing agents, strong bases. | [Water Solubility ]
Soluble in hot water and alcohol. | [Merck ]
14,7315 | [BRN ]
907309 | [CAS DataBase Reference]
103-85-5(CAS DataBase Reference) | [EPA Substance Registry System]
Phenylthiourea (103-85-5) |
| Safety Data | Back Directory | [Hazard Codes ]
T+ | [Risk Statements ]
R28:Very Toxic if swallowed.
R43:May cause sensitization by skin contact. | [Safety Statements ]
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2811 6.1/PG 1
| [WGK Germany ]
3
| [RTECS ]
YU1400000
| [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
I | [HS Code ]
29309090 | [Hazardous Substances Data]
103-85-5(Hazardous Substances Data) | [Toxicity]
LD50 in rats, rabbits (mg/kg): 3, 40 orally (Scheline) |
| Hazard Information | Back Directory | [General Description]
Needle-like crystals. Used in the manufacture of rodenticides and in medical genetics. | [Reactivity Profile]
PHENYLTHIOUREA(103-85-5) is incompatible with strong oxidizers, strong acids and strong bases. PHENYLTHIOUREA(103-85-5) emits toxic fumes on contact with acid fumes. | [Air & Water Reactions]
Insoluble in water. | [Health Hazard]
PHENYLTHIOUREA is classified as extremely toxic. The probable oral lethal dose is 5-50 mg/kg or between 7 drops and 1 teaspoon for a 70 kg (150 lb.) person. | [Potential Exposure]
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Contact with acids or acid fumes produces toxic fumes of sulfur oxide. | [Fire Hazard]
Dangerous disaster hazard; emits toxic fumes of oxides of sulfur and nitrogen when heated to decomposition. Avoid acids or acid fumes. | [First aid]
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN2767 Phenyl urea pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. | [Incompatibilities]
If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. Medical observation is recommended for 2448 hours after breathing overexposure, as pulmonary edema may be delayed. As first aid for pulmonary edema, a doctor or authorized paramedic may consider administering a drug or other inhalation therapy.
| [Chemical Properties]
N-phenylthiourea is a colorless crystalline solid. | [Chemical Properties]
white crystalline powder | [Waste Disposal]
In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office. | [Uses]
In medical genetics. | [Definition]
ChEBI: N-phenylthiourea is a member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by a phenyl group. Depending on their genetic makeup, humans find it either very bitter-tasting or tasteless. This unusual property resulted in N-phenylthiourea being used in paternity testing prior to the advent of DNA testing. It has a role as an EC 1.14.18.1 (tyrosinase) inhibitor. It is functionally related to a thiourea. | [Purification Methods]
Crystallise the thiourea from water and dry it at 100o in air. [Beilstein 12 IV 804.] |
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