| Identification | More | [Name]
5-Bromoindole | [CAS]
10075-50-0 | [Synonyms]
5-BI
5-BROMO-1H-INDOLE
5-BROMOINDOLE
RARECHEM AH BS 0082
5-Bromindole
5-bromonindole
5-Bromide indole
Bromoindole-99%
5-Bromoindole99%
5-Bromoindole 99%
5-BROMOBENZOTHOAZOLE
5-BROMOINDAN-1-ONE
5-BROMO INDOLE pure
1H-Indole, 5-bromo- | [EINECS(EC#)]
233-208-7 | [Molecular Formula]
C8H6BrN | [MDL Number]
MFCD00005670 | [Molecular Weight]
196.04 | [MOL File]
10075-50-0.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light brown powder or chunks | [Melting point ]
90-92 °C (lit.) | [Boiling point ]
228.5°C (rough estimate) | [density ]
1.5466 (rough estimate) | [refractive index ]
1.6550 (estimate) | [storage temp. ]
-20°C | [solubility ]
126mg/l (calculated) | [form ]
Powder or Chunks | [pka]
16.04±0.30(Predicted) | [color ]
White to light brown | [Detection Methods]
HPLC,NMR | [BRN ]
112877 | [InChI]
InChI=1S/C8H6BrN/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5,10H | [InChIKey]
VXWVFZFZYXOBTA-UHFFFAOYSA-N | [SMILES]
N1C2=C(C=C(Br)C=C2)C=C1 | [CAS DataBase Reference]
10075-50-0(CAS DataBase Reference) | [EPA Substance Registry System]
10075-50-0(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HS Code ]
29339990 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light brown powder or chunks | [Uses]
A potential inhibitor of GSK-3 | [Purification Methods]
Purify it by steam distillation from a faintly alkaline solution. Cool the aqueous distillate, collect the solid, dry it in a vacuum desiccator over P2O5 and recrystallise it from aqueous EtOH (35% EtOH) or pet ether/Et2O. UV in MeOH has at 279, 287 and 296nm (log 3.70, 3.69 and 3.53). The picrate has m 137-138o(dec) (from max Et2O/pet ether). [UV: Thesing et al. Chem Ber 95 2205 1962, UV and NMR: Lallemand & Bernath Bull Soc Chim Fr 4091 1970, Beilstein 20/7 V 36.] |
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