| Identification | Back Directory | [Name]
LCL-161 | [CAS]
1005342-46-0 | [Synonyms]
CS-987
LCL-161
LCL-161; LCL161
LCL-161 USP/EP/BP
LCL161, inhibitor of Apoptosis Protein (IAP) family of proteins
LCL161, 98%, inhibitor of Apoptosis Protein (IAP) family of proteins
(S)-N-((S)-1-Cyclohexyl-2-((S)-2-(4-(4-fluorobenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)
N-[(1S)-1-Cyclohexyl-2-{(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]-1-pyrrolidinyl}-2-oxoethyl]-N2-MethylalaninaMide
(2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-propanamide
N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-(2S)-propanamide
Propanamide, N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-, (2S)-
(2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-propanamide LCL 161 | [Molecular Formula]
C26H33FN4O3S | [MDL Number]
MFCD23160049 | [MOL File]
1005342-46-0.mol | [Molecular Weight]
500.629 |
| Chemical Properties | Back Directory | [Boiling point ]
713.7±60.0 °C(Predicted) | [density ]
1.245±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
≥25.05 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH | [form ]
solid | [pka]
14.25±0.46(Predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Description]
LCL-161 is a small molecule Smac mimetic that inhibits multiple inhibitor of apoptosis (IAP) family proteins. | [Uses]
LCL 161 is a second mitochondria-derived activator of caspases (SMAC) inhibitor used to prolong patient survival by increasing apoptosis of anti-tumor drugs. |
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| Company Name: |
DKMbiochem.Co. Ltd Gold
|
| Tel: |
15901859516 |
| Website: |
http://www.dkmbiochem.com/ |
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