Xylitol synthesis

8synthesis methods

Product Name:Xylitol
CAS Number:87-99-0
Molecular formula:C5H12O5
Molecular Weight:152.15

Xylitol occurs naturally in many fruits and berries, although extraction from such sources is not considered to be commercially viable. Industrially, xylitol is most commonly derived from various types of hemicellulose obtained from such sources as wood, corn cobs, cane pulp, seed hulls, and shells. These materials typically contain 20–35% xylan, which is readily converted to xylose (wood sugar) by hydrolysis. This xylose is subsequently converted to xylitol via hydrogenation (reduction). Following the hydrogenation step, there are a number of separation and purification steps that ultimately yield high-purity xylitol crystals. The nature of this process, and the stringent purification procedures employed, result in a finished product with a very low impurity content. Potential impurities that may appear in small quantities are mannitol, sorbitol, galactitol, or arabitol.
Less commonly employed methods of xylitol manufacture include the conversion of glucose (dextrose) to xylose followed by hydrogenation to xylitol, and the microbiological conversion of xylose to xylitol.

58-86-6 Synthesis

58-86-6
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87-99-0
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Yield:87-99-0 100%

Reaction Conditions:

with hydrogen in lithium hydroxide monohydrate at 120; under 15001.5 Torr; for 0.166667 h;Temperature;Pressure;

Steps:

13 Example: 13

To 0.5 g of xylose in 40 ml of H20, HRO/Na-β catalyst (50 mg) was added in a reactorvessel. The reactor vessel was then heated at 120 °C for 10 mm under H2 pressure (20 bar).After completion of the reaction, the catalyst was separated by using centrifuge and theobtained clear product mixture was analyzed by UHPLC. The reaction gave 100% conversionof xylose with 100% yield of xylitol.

References:

WO2017/60922,2017,A1 Location in patent:Page/Page column 13; 14; 20; 21; 26

58-86-6 Synthesis

58-86-6
443 suppliers
$5.00/25g

488-82-4 Synthesis