Trityl Olmesartan Medoxomil synthesis
- Product Name:Trityl Olmesartan Medoxomil
- CAS Number:1020157-01-0
- Molecular formula:C48H44N6O6
- Molecular Weight:800.9
58954-23-7
160 suppliers
$100.00/50 mg
1020157-01-0
65 suppliers
$145.00/10mg
Yield:-
Steps:
Multi-step reaction with 5 steps
1: 86 percent / HCl / Ambient temperature
2: 95 percent / diethyl ether; CH2Cl2 / 1 h / 10 - 15 °C
3: 1.) t-BuOK / 1.) DMA, 0 deg C, 10 min, 2.) DMA, RT, 1 h
4: LiOH*H2O / dioxane; H2O / 20 h / Ambient temperature
5: 88 percent / K2CO3 / N,N-dimethyl-acetamide / 4 h / 20 - 50 °C
References:
Yanagisawa, Hiroaki;Amemiya, Yoshiya;Kanazaki, Takuro;Shimoji, Yasuo;Fujimoto, Koichi;Kitahara, Yoshiko;Sada, Toshio;Mizuno, Makoto;Ikeda, Masahiro;Miyamoto, Shuichi;Furukawa, Youji;Koike, Hiroyuki [Journal of Medicinal Chemistry,1996,vol. 39,# 1,p. 323 - 338]
752179-89-8
35 suppliers
inquiry
80841-78-7
531 suppliers
$10.00/250mg
1020157-01-0
65 suppliers
$145.00/10mg
80841-78-7
531 suppliers
$10.00/250mg
172875-59-1
46 suppliers
inquiry
1020157-01-0
65 suppliers
$145.00/10mg
![5-[4'-(Bromomethyl)-[1,1'-biphenyl]-2-yl]-2-(triphenylmethyl)-2H-tetrazole](/CAS/GIF/133051-88-4.gif)
133051-88-4
94 suppliers
$71.00/50 mg
144689-93-0
478 suppliers
$16.00/5g
1020157-01-0
65 suppliers
$145.00/10mg
![1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-, sodium salt (1:1)](/CAS/20211123/GIF/1048948-16-8.gif)
1048948-16-8
0 suppliers
inquiry
80841-78-7
531 suppliers
$10.00/250mg
1020157-01-0
65 suppliers
$145.00/10mg