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ChemicalBook CAS DataBase List TRIMETHYLSILYLMETHYLMAGNESIUM CHLORIDE
13170-43-9

TRIMETHYLSILYLMETHYLMAGNESIUM CHLORIDE synthesis

2synthesis methods
From (chloromethyl)trimethylsilane and magnesium in an ethereal solvent.
-

Yield:-

Reaction Conditions:

in tetrahydrofuran at 20; for 3 h;

Steps:

52
Example 52; (Trimethylsilyl)methylmagnesium chloride; To a well-stirred mixture of magnesium turnings (3.75 g, 154.04 mmol) in 120 mL of THF was added (chloromethyl)trimethylsilane (9.44 g, 77.02 mmol) in 37 mL of THF. The mixture was stirred for 3 h at room temperature to ensure complete generation of the organomagnesium species and was then used fresh.

References:

Isis Innovation Limited US2007/142632, 2007, A1 Location in patent:Page/Page column 35

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