ChemicalBook CAS DataBase List TRIMETHYLPHOSPHINE OXIDE

TRIMETHYLPHOSPHINE OXIDE synthesis

4synthesis methods

Product Name:TRIMETHYLPHOSPHINE OXIDE
CAS Number:676-96-0
Molecular formula:C3H9OP
Molecular Weight:92.08

676-58-4 Synthesis

676-58-4
285 suppliers
$15.00/25ml

676-96-0
90 suppliers
$29.00/1g

Yield:676-96-0 95%

Reaction Conditions:

with copper dichloride;trichlorophosphate in tetrahydrofuran;toluene at 5; for 2 h;Temperature;Solvent;Reagent/catalyst;

Steps:

1.2
Step 1) the resulting reaction liquid-cooled is cooled to 5 °C time, adding 2g anhydrous copper chloride, and then is dripped slowly into the 51g phosphorus oxychloride, after the dipping stirring 2 hours (dropwise process maintain the temperature in the 5 °C), then adding 200 ml of water and 10 ml of the mass fraction of 35% hydrochloric acid, the 2 hour later, liquid magnesium chloride is separated, the oil reservoir vacuum distillation, to be 4/5 when the liquid is boiled, cooling crystallization, to filtering and drying 29.1g trimethylacetophenone method, the yield is 95.0%, purity of 99.5%.

References:

Shandong Weitian Fine Chemical Technology Co., Ltd.;Liu, yu zhen;Liu, yu qiang;Huang, shou chao;Li, zhang bo;Liu, gan;Liu, yang sheng CN105566388, 2016, A Location in patent:Paragraph 0014

FullText

2404-55-9 Synthesis