ChemicalBook CAS DataBase List TRIETHYLENE GLYCOL MONO-N-DODECYL ETHER

TRIETHYLENE GLYCOL MONO-N-DODECYL ETHER synthesis

6synthesis methods

Product Name:TRIETHYLENE GLYCOL MONO-N-DODECYL ETHER
CAS Number:3055-94-5
Molecular formula:C18H38O4
Molecular Weight:318.49

2050-77-3
137 suppliers
$19.00/5g

112-27-6 Synthesis

112-27-6
759 suppliers
$6.00/100g

3055-94-5
77 suppliers
$357.00/5mL

Yield:3055-94-5 48%

Reaction Conditions:

with sodium hydride in N,N-dimethyl-formamide at 0; for 2 h;Inert atmosphere;

Steps:

4 The general method of synthesis of P
General procedure: Under argon protection conditions,Add iodoalkane (1 eq.) to a solution of triethylene glycol or triethylene glycol (1 eq.) in DMF (40 mL).The mixture was cooled to 0 ° C,Add sodium hydride (1.5 eq. 60% in mineral oil) and stir for 2 h.Quenched with water and extracted with ethyl acetate (20 mL×2).The ethyl acetate phases were combined and washed with brine.Then dried over anhydrous sodium sulfate and concentrated to give a crude P product.Purified by silica gel column chromatography (ethyl acetate-hexane)The sample was taken immediately for the next reaction.

References:

Heilongjiang 81 Farming University;Li Jing;Shen Guinan;Zhang Ying CN110066269, 2019, A Location in patent:Paragraph 0049; 0061-0063

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143-15-7 Synthesis