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ChemicalBook CAS DataBase List trans-Cinnamaldehyde
14371-10-9

trans-Cinnamaldehyde synthesis

12synthesis methods
-

Yield:14371-10-9 91%

Reaction Conditions:

with 1-hydroxy-1H-1,2,3-benziodoxathiole 1,3,3-trioxide;Oxone;cetyltrimethylammonim bromide in water at 20; for 2 h;Green chemistry;chemoselective reaction;

Steps:

IBS-catalysed alcohol oxidation in CTAB micelle; general procedure

General procedure: The alcohol (2 mmol) was added to a solution of IBS (0.02 mmol, 0.01 eq), oxone (2.2 mmol, 1.1 equiv.) and 3 wt% CTAB solution (5 mL). The mixture was stirred at room temperature. The reaction was monitored by TLC. After completion, the solution was extracted with CH2Cl2 (3 × 10 mL). The combined organic phase was then filtered through a pad of silica gel and evaporated under vacuum to afford the desired product.

References:

Liu, Yangyang;Wang, Boliang [Journal of Chemical Research,2014,vol. 38,# 7,p. 427 - 431]

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