ChemicalBook CAS DataBase List Tetrakis(4-aminophenyl)methane

Tetrakis(4-aminophenyl)methane synthesis

6synthesis methods

Product Name:Tetrakis(4-aminophenyl)methane
CAS Number:60532-63-0
Molecular formula:C25H24N4
Molecular Weight:380.48

synthesis of Tetrakis(4-aminophenyl)methane: Tetrakis-(4-nitrophenyl)methane (1.5 g, 3 mmol) was dissolved in tetrahydrofuran (100 ml), and Raney nickel (10 g) was added to the solution while stirring under nitrogen. Hydrazine monohydrate (2 g, 0.04 mol) was slowly added via syringe, and the mixture was refluxed for 4 h. The mixture was filtered while hot and washed with ethanol. The filtrate was dried in vacuo. The crude product was subsequently washed with ethanol (50 ml) and dried in vacuo to afford Tetrakis(4-aminophenyl)methane as a white solid (0.92 g, 81% yield).
synthesis of Tetrakis(4-aminophenyl)methane

630-76-2 Synthesis

630-76-2
173 suppliers
$16.00/250mg

60532-63-0
126 suppliers
$22.00/250mg

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 38 percent / acetic anhydride; acetic acid; nitric acid / -10 °C
2: 61.3 percent / hydrazine monohydrate; Raney-nickel / tetrahydrofuran / 3 h / Heating

References:

Ganesan, Palaniswamy;Yang, Xiaoniu;Loos, Joachim;Savenije, Tom J.;Abellon, Ruben D.;Zuilhof, Han;Sudhoelter, Ernst J. R. [Journal of the American Chemical Society,2005,vol. 127,# 42,p. 14530 - 14531]

60532-62-9 Synthesis