tert-butyl 4-(bromomethyl)-1H-indole-1-carboxylate synthesis
- Product Name:tert-butyl 4-(bromomethyl)-1H-indole-1-carboxylate
- CAS Number:220499-13-8
- Molecular formula:C14H16BrNO2
- Molecular Weight:310.19
59382-59-1
256 suppliers
$15.00/5g
220499-13-8
25 suppliers
$295.00/250MG
Yield:-
Steps:
Multi-step reaction with 5 steps
1: dimethylformamide / 12 h / 120 °C
2: H2 / 10 percent Pd/C / benzene / 12 h / 2844.31 Torr / Ambient temperature
3: 100 percent / DMAP / acetonitrile / 12 h / Ambient temperature
4: 88 percent / DIBAL / diethyl ether; CH2Cl2 / 0.5 h / -78 °C
5: 84 percent / PBr3 / diethyl ether; CH2Cl2 / 0.5 h / 0 °C
References:
Fauq, Abdul H.;Hong, Feng;Cusack, Bernadette;Tyler, Beth M.;Ping-Pang, Yuan;Richelson, Elliott [Tetrahedron Asymmetry,1998,vol. 9,# 23,p. 4127 - 4134]
220499-12-7
22 suppliers
$70.00/50 mg
220499-13-8
25 suppliers
$295.00/250MG
39830-66-5
297 suppliers
$14.00/1g
220499-13-8
25 suppliers
$295.00/250MG
1975-50-4
442 suppliers
$18.00/25g
220499-13-8
25 suppliers
$295.00/250MG
73816-11-2
8 suppliers
inquiry
220499-13-8
25 suppliers
$295.00/250MG