(R)-(-)-5-OXOTETRAHYDROFURAN-2-CARBOXYLIC ACID synthesis
- Product Name:(R)-(-)-5-OXOTETRAHYDROFURAN-2-CARBOXYLIC ACID
- CAS Number:53558-93-3
- Molecular formula:C5H6O4
- Molecular Weight:130.1
328-50-7
564 suppliers
$6.00/25g
21461-84-7
201 suppliers
$19.00/250mg
53558-93-3
115 suppliers
$14.00/250mg
Yield:52 % ee
Reaction Conditions:
with nickel trifluoromethanesulfonate;1,2-bis((2S,5S)-2,5-diphenylphospholan-1-yl)ethane;2,2,2-trifluoroethanol;hydrogen at 65; under 38002.6 Torr; for 24 h;Schlenk technique;Overall yield = 95 percentChromat.; enantioselective reaction;
References:
Deng, Chen-Qiang;Deng, Jin;Fu, Yao;Gan, Li-Jin;Liu, Jiao;Luo, Jia-Hao [Angewandte Chemie - International Edition,2022,vol. 61,# 15,art. no. E202115983][Angew. Chem.,2022,vol. 134,# 15] Location in patent:supporting information
6893-26-1
464 suppliers
$6.00/10g
53558-93-3
115 suppliers
$14.00/250mg
56-86-0
815 suppliers
$5.00/25g
53558-93-3
115 suppliers
$14.00/250mg