ChemicalBook CAS DataBase List PORPHINE

PORPHINE synthesis

5synthesis methods

Product Name:PORPHINE
CAS Number:101-60-0
Molecular formula:C20H14N4
Molecular Weight:310.35

109-97-7 Synthesis

109-97-7
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$9.00/5 g

100-52-7 Synthesis

100-52-7
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$17.30/2g

101-60-0
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917-23-7
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$13.00/250mg

Yield:101-60-0 15%

Reaction Conditions:

with acetic acid;propionic acid at 140; for 0.5 h;

Steps:

Synthesis of N3 (meso-Tetraphenylporphyrin), C44H30N4 (H2TPP)
Acetic acid and propionic acid were used as solvents for the synthesis of H2TPP. More pure H2TPP with improved yield was obtained when propionic acid was used as solvent. Acetic/propionic acid (75 mL) was placed in a 250 mL round bottom flask. Benzaldehyde (5.0 mL, 49 mmol) was dissolved in propionic acid. The benzaldehyde solution was added during a time period of 3-4 minutes. The reaction mixture was refluxed for 30 minutes and then cooled to room temperature. After cooling, the reaction mixture was neutralized by using 50 mL of 10 N NaOH. The fractions were extracted by column chromatography using hexane: CH2Cl2 (8:2). An additional product formed from this reaction was chlorin with a yield of 15 %.

References:

Naveed Umar, Muhammad;Ur. Rashid, Haroon;Gul Sayed, Mian;Karim, Nasiara;Ghaffar, Rukhsana;Antonio Utrera Martines, Marco;Shoaib, Mohammad [Revue Roumaine de Chimie,2015,vol. 60,# 9,p. 861 - 866]

27472-36-2 Synthesis