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ChemicalBook CAS DataBase List PHENYL AZIDE
622-37-7

PHENYL AZIDE synthesis

10synthesis methods
-

Yield:622-37-7 100%

Reaction Conditions:

with tert.-butylnitrite;trimethylsilylazide in acetonitrile at 20; for 1 h;Inert atmosphere;

Steps:

Synthesis of Aromatic Azides; General Procedure
General procedure: A solution of aromatic amine (1.0 equiv) in MeCN (2 mL/mmol) wascooled to 0 °C and t-BuONO (1.5 equiv) followed by TMSN3 (1.5 equiv)were added dropwise. The resulting solution was stirred at r.t. for 1 h.The mixture was concd under vacuum, diluted with hexane, and filteredon a short pad of silica gel. The azide was obtained in quantitativeyield and was used without further purification and isolation.

References:

Zanato, Chiara;Cascio, Maria Grazia;Lazzari, Paolo;Pertwee, Roger;Testa, Andrea;Zanda, Matteo [Synthesis,2015,vol. 47,# 6,art. no. 8407,p. 817 - 826]

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