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ChemicalBook CAS DataBase List perfluorohexane-1-sulphonic acid
355-46-4

perfluorohexane-1-sulphonic acid synthesis

6synthesis methods
-

Yield:355-46-4 14.2 g

Reaction Conditions:

with hydrogenchloride in water;acetone at 20; for 1 h;

Steps:

5.a (a) Preparation of Tridecafluorohexane-1 -Sulfonic Acid
To a solution of potassium tridecafluorohexane-1 -Sulfonate (15.3 g, 30.0 mmol, 1.0 eq) in acetone (300 mL) was added HCI (37%, 2.25 mL, 33.0 mmol, 1.1 eq) at room temperature. The reaction was stirred at room temperature lh. The mixture was filtered and concentrated to dryness. The residue was diluted with ethyl acetate and washed with water. The organic phase was separated, dried with sodium sulfate, and concentrated to afford (0442) tridecafluorohexane-1 -sulfonic acid (14.2 g) as a white solid.

References:

THERACAINE LLC;SAWAN, Samuel, P. WO2019/89523, 2019, A1 Location in patent:Page/Page column 85

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