天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

40167-20-2

N-(METHYLTHIO)PHTHALIMIDE 97 synthesis

4synthesis methods
-

Yield:40167-20-2 96.22%

Reaction Conditions:

with pyridine in ethanol at 10 - 40; for 36 h;Temperature;Reagent/catalyst;Solvent;

Steps:

1-4 Example 4

In a 2000ml four-necked flask equipped with a mechanical stirrer, water bath, dropping funnel, reflux condenser and thermometer, add 80g (0.49mol) N-hydroxyphthalimide, 8g pyridine and 800g anhydrous ethanol, 70g (1.45mol) methyl mercaptan was added dropwise with stirring. With the dropping of methyl mercaptan, the system slightly exothermed. Control the dropping rate so that the system temperature does not exceed 10°C. After the addition was completed, the reaction was stirred at 40°C for 36 hours. After the heat preservation is over, the reaction solution is transferred to a rotary evaporator to distill off excess methyl mercaptan and ethanol. Add 200ml of new methanol to the bottom of the bottle and heat until it is transparent. Crystallize at 0°C for 5 hours. Pour out and filter, wash the filter cake with water until it is neutral, and dry to obtain 91 g of white needle-like crystalline powder, which is N-methylthio phthalimide. The melting range is 177.0-178.3, and the content measured by gas chromatography external standard method is 98.89%. The molar yield based on N-hydroxyphthalimide was 96.22%.

References:

CN111393353,2020,A Location in patent:Paragraph 0008; 0010-0017

N-(METHYLTHIO)PHTHALIMIDE 97 Related Search: