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ChemicalBook CAS DataBase List N-MALEIMIDOMETHANOL
5063-96-7

N-MALEIMIDOMETHANOL synthesis

1synthesis methods
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Yield:-

Steps:

P.6 1-Hydroxymethyl-pyrrole-2,5-dione
PREPARATION EXAMPLE 6 1-Hydroxymethyl-pyrrole-2,5-dione Maleimide (2.0 g) and 10% formaline (6.8 g) were stirred at 100° C. for 60 minutes. The reaction was let to cool and then kept overnight at 4° C. The product was filtered, washed with water and ethanol. Yield: 1.3 g, melting point 96,5-97° C. 1H-NMR (DMSO-d6, 400 MHz): 7.07 (s,2H), 6.27 (t,1H, J=7 Hz), 4.78 (d,2H, J=7 Hz).

References:

B?ckstr?m, Reijo;Pystynen, Jarmo;Lotta, Timo;Ovaska, Martti;Taskinen, Jyrki US2004/34011, 2004, A1

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